Effect of Cepharanthin in preventing radiation induced normal tissue damage in prostate cancer

Satoshi Nomoto, Hajime Imada, Takayuki Ohguri, Katsuya Yahara, Fumio Kato, Tomoaki Morioka, Yukunori Korogi

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4 Citations (Scopus)

Abstract

A total of 97 patients with prostate cancer who underwent radiotherapy were retrospectively reviewed to analyze the protective efficacy of Cepharanthin for acute or late toxicity to the bladder/urethra and rectum. Cepharanthin administrations were divided into 3 groups: intravenous, oral, and non-administration. Acute urinary toxicity was significantly milder for the intravenous group than for the oral and non-administration groups. The protective efficacy of Cepharanthin was not approved for acute rectal toxicity, but late rectal toxicity was significantly milder for the intravenous group than for the oral group. Intravenous Cepharanthin administration may prevent acute or late toxicity by radiotherapy for prostate cancer.

Original languageEnglish
Pages (from-to)1063-1066
Number of pages4
JournalGan to kagaku ryoho. Cancer & chemotherapy
Volume31
Issue number7
Publication statusPublished - Jan 1 2004

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All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Nomoto, S., Imada, H., Ohguri, T., Yahara, K., Kato, F., Morioka, T., & Korogi, Y. (2004). Effect of Cepharanthin in preventing radiation induced normal tissue damage in prostate cancer. Gan to kagaku ryoho. Cancer & chemotherapy, 31(7), 1063-1066.