Effect of Co-Solvent on the solubility of ginger bioactive compounds in water using COSMO-RS calculations

Syaripah Zaimah Syed Jaapar, Yoshio Iwai, Noor Azian Morad

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

The effects of co-solvent to the solubility of ginger bioactive compounds, 6-gingerol, 6- shogaol, 8-gingerol and 10-gingerol in hot water were calculated using the conductor-like screening model for real solvent (COSMO-RS). In this work, ethanol was used as the co-solvent. The σ- profiles of the molecules were calculated using Gaussian software and the solubility were calculated using the COSMO-RS method. The solubility of these ginger bioactive compounds were calculated at 50 to 150°C.The amounts of ethanol used were 0 mol (binary system), 0.005, 0.010 and 0.015 mol. The results show that when the concentration (mole fraction of ethanol) of co-solvent increases, the solubility of ginger bioactive compounds increase. While the temperature increases, the concentration (mole fraction of ethanol) of co-solvent decreases.

Original languageEnglish
Title of host publicationAdvanced Development in Automation, Materials and Manufacturing
PublisherTrans Tech Publications Ltd
Pages174-178
Number of pages5
ISBN (Print)9783038352259
DOIs
Publication statusPublished - Jan 1 2014
Event2014 International Conference on Mechatronics, Materials and Manufacturing, ICMMM 2014 - Chengdu, China
Duration: Aug 2 2014Aug 4 2014

Publication series

NameApplied Mechanics and Materials
Volume624
ISSN (Print)1660-9336
ISSN (Electronic)1662-7482

Other

Other2014 International Conference on Mechatronics, Materials and Manufacturing, ICMMM 2014
CountryChina
CityChengdu
Period8/2/148/4/14

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Fingerprint Dive into the research topics of 'Effect of Co-Solvent on the solubility of ginger bioactive compounds in water using COSMO-RS calculations'. Together they form a unique fingerprint.

Cite this