Effect of Co-Solvent on the solubility of ginger bioactive compounds in water using COSMO-RS calculations

Syaripah Zaimah Syed Jaapar, Yoshio Iwai, Noor Azian Morad

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

The effects of co-solvent to the solubility of ginger bioactive compounds, 6-gingerol, 6- shogaol, 8-gingerol and 10-gingerol in hot water were calculated using the conductor-like screening model for real solvent (COSMO-RS). In this work, ethanol was used as the co-solvent. The σ- profiles of the molecules were calculated using Gaussian software and the solubility were calculated using the COSMO-RS method. The solubility of these ginger bioactive compounds were calculated at 50 to 150°C.The amounts of ethanol used were 0 mol (binary system), 0.005, 0.010 and 0.015 mol. The results show that when the concentration (mole fraction of ethanol) of co-solvent increases, the solubility of ginger bioactive compounds increase. While the temperature increases, the concentration (mole fraction of ethanol) of co-solvent decreases.

Original languageEnglish
Title of host publicationAdvanced Development in Automation, Materials and Manufacturing
PublisherTrans Tech Publications Ltd
Pages174-178
Number of pages5
ISBN (Print)9783038352259
DOIs
Publication statusPublished - Jan 1 2014
Event2014 International Conference on Mechatronics, Materials and Manufacturing, ICMMM 2014 - Chengdu, China
Duration: Aug 2 2014Aug 4 2014

Publication series

NameApplied Mechanics and Materials
Volume624
ISSN (Print)1660-9336
ISSN (Electronic)1662-7482

Other

Other2014 International Conference on Mechatronics, Materials and Manufacturing, ICMMM 2014
CountryChina
CityChengdu
Period8/2/148/4/14

Fingerprint

Screening
Solubility
Ethanol
Water
Molecules
Temperature

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Jaapar, S. Z. S., Iwai, Y., & Morad, N. A. (2014). Effect of Co-Solvent on the solubility of ginger bioactive compounds in water using COSMO-RS calculations. In Advanced Development in Automation, Materials and Manufacturing (pp. 174-178). (Applied Mechanics and Materials; Vol. 624). Trans Tech Publications Ltd. https://doi.org/10.4028/www.scientific.net/AMM.624.174

Effect of Co-Solvent on the solubility of ginger bioactive compounds in water using COSMO-RS calculations. / Jaapar, Syaripah Zaimah Syed; Iwai, Yoshio; Morad, Noor Azian.

Advanced Development in Automation, Materials and Manufacturing. Trans Tech Publications Ltd, 2014. p. 174-178 (Applied Mechanics and Materials; Vol. 624).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Jaapar, SZS, Iwai, Y & Morad, NA 2014, Effect of Co-Solvent on the solubility of ginger bioactive compounds in water using COSMO-RS calculations. in Advanced Development in Automation, Materials and Manufacturing. Applied Mechanics and Materials, vol. 624, Trans Tech Publications Ltd, pp. 174-178, 2014 International Conference on Mechatronics, Materials and Manufacturing, ICMMM 2014, Chengdu, China, 8/2/14. https://doi.org/10.4028/www.scientific.net/AMM.624.174
Jaapar SZS, Iwai Y, Morad NA. Effect of Co-Solvent on the solubility of ginger bioactive compounds in water using COSMO-RS calculations. In Advanced Development in Automation, Materials and Manufacturing. Trans Tech Publications Ltd. 2014. p. 174-178. (Applied Mechanics and Materials). https://doi.org/10.4028/www.scientific.net/AMM.624.174
Jaapar, Syaripah Zaimah Syed ; Iwai, Yoshio ; Morad, Noor Azian. / Effect of Co-Solvent on the solubility of ginger bioactive compounds in water using COSMO-RS calculations. Advanced Development in Automation, Materials and Manufacturing. Trans Tech Publications Ltd, 2014. pp. 174-178 (Applied Mechanics and Materials).
@inproceedings{89a9eb3eab1e485c8cb7a64b9bd5f3f6,
title = "Effect of Co-Solvent on the solubility of ginger bioactive compounds in water using COSMO-RS calculations",
abstract = "The effects of co-solvent to the solubility of ginger bioactive compounds, 6-gingerol, 6- shogaol, 8-gingerol and 10-gingerol in hot water were calculated using the conductor-like screening model for real solvent (COSMO-RS). In this work, ethanol was used as the co-solvent. The σ- profiles of the molecules were calculated using Gaussian software and the solubility were calculated using the COSMO-RS method. The solubility of these ginger bioactive compounds were calculated at 50 to 150°C.The amounts of ethanol used were 0 mol (binary system), 0.005, 0.010 and 0.015 mol. The results show that when the concentration (mole fraction of ethanol) of co-solvent increases, the solubility of ginger bioactive compounds increase. While the temperature increases, the concentration (mole fraction of ethanol) of co-solvent decreases.",
author = "Jaapar, {Syaripah Zaimah Syed} and Yoshio Iwai and Morad, {Noor Azian}",
year = "2014",
month = "1",
day = "1",
doi = "10.4028/www.scientific.net/AMM.624.174",
language = "English",
isbn = "9783038352259",
series = "Applied Mechanics and Materials",
publisher = "Trans Tech Publications Ltd",
pages = "174--178",
booktitle = "Advanced Development in Automation, Materials and Manufacturing",

}

TY - GEN

T1 - Effect of Co-Solvent on the solubility of ginger bioactive compounds in water using COSMO-RS calculations

AU - Jaapar, Syaripah Zaimah Syed

AU - Iwai, Yoshio

AU - Morad, Noor Azian

PY - 2014/1/1

Y1 - 2014/1/1

N2 - The effects of co-solvent to the solubility of ginger bioactive compounds, 6-gingerol, 6- shogaol, 8-gingerol and 10-gingerol in hot water were calculated using the conductor-like screening model for real solvent (COSMO-RS). In this work, ethanol was used as the co-solvent. The σ- profiles of the molecules were calculated using Gaussian software and the solubility were calculated using the COSMO-RS method. The solubility of these ginger bioactive compounds were calculated at 50 to 150°C.The amounts of ethanol used were 0 mol (binary system), 0.005, 0.010 and 0.015 mol. The results show that when the concentration (mole fraction of ethanol) of co-solvent increases, the solubility of ginger bioactive compounds increase. While the temperature increases, the concentration (mole fraction of ethanol) of co-solvent decreases.

AB - The effects of co-solvent to the solubility of ginger bioactive compounds, 6-gingerol, 6- shogaol, 8-gingerol and 10-gingerol in hot water were calculated using the conductor-like screening model for real solvent (COSMO-RS). In this work, ethanol was used as the co-solvent. The σ- profiles of the molecules were calculated using Gaussian software and the solubility were calculated using the COSMO-RS method. The solubility of these ginger bioactive compounds were calculated at 50 to 150°C.The amounts of ethanol used were 0 mol (binary system), 0.005, 0.010 and 0.015 mol. The results show that when the concentration (mole fraction of ethanol) of co-solvent increases, the solubility of ginger bioactive compounds increase. While the temperature increases, the concentration (mole fraction of ethanol) of co-solvent decreases.

UR - http://www.scopus.com/inward/record.url?scp=84906972006&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84906972006&partnerID=8YFLogxK

U2 - 10.4028/www.scientific.net/AMM.624.174

DO - 10.4028/www.scientific.net/AMM.624.174

M3 - Conference contribution

SN - 9783038352259

T3 - Applied Mechanics and Materials

SP - 174

EP - 178

BT - Advanced Development in Automation, Materials and Manufacturing

PB - Trans Tech Publications Ltd

ER -