Effect of conformational changes and differences of proteins on frictional properties of poly(vinyl alcohol) hydrogel

Kazuhiro Nakashima, Yoshinori Sawae, Teruo Murakami

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

In this study, albumin or γ-globulin, both of which are included in natural synovial fluid, was used as an additive into lubricants to investigate the ability to reduce the friction for poly(vinyl alcohol) hydrogel in mixed lubrication. It was found from a measurement in circular dichroism that albumin contains a large amount of α-helix structure and γ-globulin contains a large amount of β-sheet structure. The lubricant containing only albumin showed low friction compared to the lubricant containing only γ-globulin. The effect of protein boundary film was clarified by changing lubricant. Albumin kept the friction low after changing from γ-globulin used at initial rubbing, but γ-globulin increased the friction after changing from albumin at initial rubbing. From a sliding distance of 600 m, albumin showed lower friction but γ-globulin showed higher friction. Therefore, in the case of friction decreasing, γ-globulin forms a tight adsorbed layer and subsequently albumin forms a layer with low shearing strength. Hence, it is important to apply the adsorption layer of γ-globulin at the bottom and make a layered structure composed of albumin and γ-globulin to reduce both friction and wear.

Original languageEnglish
Pages (from-to)1423-1427
Number of pages5
JournalTribology International
Volume40
Issue number10-12 SPEC. ISS.
DOIs
Publication statusPublished - Oct 2007

All Science Journal Classification (ASJC) codes

  • Mechanics of Materials
  • Mechanical Engineering
  • Surfaces and Interfaces
  • Surfaces, Coatings and Films

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