Effect of DBD plasma on human cells in presence of osmolytes and denaturant

Nagendra Kumar Kaushik, Pankaj Attri, Eun Ha Choi, Neha Kaushik

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Non thermal plasma is emerging as a novel tool for the treatment of living tissues for biological and medical purpose. In this study we described the effect of DBD (dielectric barrier discharge) plasma on both cancer and normal cell line in presence of osmolytes. Osmolytes having unique protective metabolic roles and also found in animal body, they are acting as antioxidants, providing redox balance, detoxifying sulfide, protect macromolecules, enhance protein folding and regulate cell volume. Based on these interesting properties of osmolytes, non thermal plasma in presence of osmolytes appears to provide a new outlook. Results of this study reveals that osmolytes in presence of plasma act as protecting agent for normal cells however, not to cancer cells in the presence of plasma. The main goal of this study is to protect normal cells from the toxic effect of DBD plasma.

Original languageEnglish
Title of host publicationPlasma Processing and Diagnostics for Life Sciences
Pages1-8
Number of pages8
DOIs
Publication statusPublished - Dec 1 2012
Externally publishedYes
Event2012 MRS Spring Meeting - San Francisco, CA, United States
Duration: Apr 9 2012Apr 13 2012

Publication series

NameMaterials Research Society Symposium Proceedings
Volume1469
ISSN (Print)0272-9172

Other

Other2012 MRS Spring Meeting
CountryUnited States
CitySan Francisco, CA
Period4/9/124/13/12

Fingerprint

plasma jets
thermal plasmas
Cells
Plasma Gases
Plasmas
cancer
cells
antioxidants
Protein folding
cultured cells
macromolecules
folding
animals
sulfides
Poisons
emerging
Sulfides
Macromolecules
proteins
Animals

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Kaushik, N. K., Attri, P., Choi, E. H., & Kaushik, N. (2012). Effect of DBD plasma on human cells in presence of osmolytes and denaturant. In Plasma Processing and Diagnostics for Life Sciences (pp. 1-8). (Materials Research Society Symposium Proceedings; Vol. 1469). https://doi.org/10.1557/opl.2012.872

Effect of DBD plasma on human cells in presence of osmolytes and denaturant. / Kaushik, Nagendra Kumar; Attri, Pankaj; Choi, Eun Ha; Kaushik, Neha.

Plasma Processing and Diagnostics for Life Sciences. 2012. p. 1-8 (Materials Research Society Symposium Proceedings; Vol. 1469).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kaushik, NK, Attri, P, Choi, EH & Kaushik, N 2012, Effect of DBD plasma on human cells in presence of osmolytes and denaturant. in Plasma Processing and Diagnostics for Life Sciences. Materials Research Society Symposium Proceedings, vol. 1469, pp. 1-8, 2012 MRS Spring Meeting, San Francisco, CA, United States, 4/9/12. https://doi.org/10.1557/opl.2012.872
Kaushik NK, Attri P, Choi EH, Kaushik N. Effect of DBD plasma on human cells in presence of osmolytes and denaturant. In Plasma Processing and Diagnostics for Life Sciences. 2012. p. 1-8. (Materials Research Society Symposium Proceedings). https://doi.org/10.1557/opl.2012.872
Kaushik, Nagendra Kumar ; Attri, Pankaj ; Choi, Eun Ha ; Kaushik, Neha. / Effect of DBD plasma on human cells in presence of osmolytes and denaturant. Plasma Processing and Diagnostics for Life Sciences. 2012. pp. 1-8 (Materials Research Society Symposium Proceedings).
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