Effect of diazinon exposure on antioxidant reactions in the silkmoth, Bombyx mori

Kohji Yamamoto, Y. Tsuji, Y. Aso, T. Hamasaki, S. Shirahata, Yoshinori Katakura

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We investigated the effects of exposure to diazinon, an organophosphate insecticide, on the expression of antioxidant and detoxification factors in the silkmoth. Exposure to diazinon resulted in induction of mRNA encoding manganese containing superoxide dismutase (SOD) and omega-class glutathione S-transferases (GST), whereas no changes were observed in catalase, other class of GST and acetylcholinesterase. Liquid chromatography showed that the amount of reactive oxygen species was increased, whereas the amount of glutathione was decreased in the silkmoth fat body after exposure to diazinon. These results suggest that SOD and omega-class GSTs can contribute to organophosphate resistance in Lepidopterans.

Original languageEnglish
Pages (from-to)320-325
Number of pages6
JournalJournal of Applied Entomology
Volume135
Issue number4
DOIs
Publication statusPublished - May 1 2011

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diazinon
Bombyx mori
glutathione transferase
antioxidants
superoxide dismutase
organophosphorus insecticides
organophosphorus compounds
fat body
acetylcholinesterase
liquid chromatography
manganese
glutathione
reactive oxygen species
catalase
Lepidoptera

All Science Journal Classification (ASJC) codes

  • Agronomy and Crop Science
  • Insect Science

Cite this

Effect of diazinon exposure on antioxidant reactions in the silkmoth, Bombyx mori. / Yamamoto, Kohji; Tsuji, Y.; Aso, Y.; Hamasaki, T.; Shirahata, S.; Katakura, Yoshinori.

In: Journal of Applied Entomology, Vol. 135, No. 4, 01.05.2011, p. 320-325.

Research output: Contribution to journalArticle

Yamamoto, Kohji ; Tsuji, Y. ; Aso, Y. ; Hamasaki, T. ; Shirahata, S. ; Katakura, Yoshinori. / Effect of diazinon exposure on antioxidant reactions in the silkmoth, Bombyx mori. In: Journal of Applied Entomology. 2011 ; Vol. 135, No. 4. pp. 320-325.
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