Effect of Gender Difference on Clinical Outcomes after CRT

Kenji Ando, Takeshi Arita, Masahiko Goya, Takeshi Kimura, Satoshi Shizuta, Takaaki Isshiki, Masakiyo Nobuyoshi

Research output: Contribution to journalArticle

Abstract

Background: Female is reported to be preferred CRT compared to male. However, precise effect of gender difference on clinical outcomes is not well known. Methods: We investigated 651 patients from CUBIC study and divided into two groups, 197 female (F group), 454 male (M group). Results: Mean follow up were 22+/15 months. F group was older (71 years vs. 68 years, p=0.01) and more likely to have wide QRS (155 ms vs. 148 ms, p=0.027) and non-ischemic etiology (83% vs. 62%, p<0.0001). M group was more likely to have diabetic (39% vs. 20%, p<0.0001), renal failure (32% vs. 17%, p<0.0001), AF (33% vs. 25%, p=0.036), VT/VF (19% vs. 12%, p=0.027) and larger LV (64mm vs. 60mm, p<0.0001). CRT-D were more common in M group (65% vs. 47%, p<0.0001). NYHA class (F group: 2.9 vs. M group: 2.9) and LVEF (F group: 29% vs. M group: 28%) were similar. There was no difference in NYHA class (2.0 vs. 2.2, p=ns) and responder rate (63% vs.62%, p=ns) at 6-month. The event free survival rates from combined death and heart failure hospitalization, ventricular arrhythmic events were significantly higher in F group (71 % vs.60% at 2-year, Log-rank p=0.038, 79% vs.67% at 2-year, Log-rank p=0.001, respectively). Conclusion: Female has fewer commodities and seems to have preferable clinical outcomes after CRT.

Original languageEnglish
Number of pages1
Journaljournal of arrhythmia
Volume27
Issue number4
DOIs
Publication statusPublished - Jan 1 2011
Externally publishedYes

Fingerprint

Disease-Free Survival
Renal Insufficiency
Hospitalization
Survival Rate
Heart Failure

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Ando, K., Arita, T., Goya, M., Kimura, T., Shizuta, S., Isshiki, T., & Nobuyoshi, M. (2011). Effect of Gender Difference on Clinical Outcomes after CRT. journal of arrhythmia, 27(4). https://doi.org/10.4020/jhrs.27.OP26_1

Effect of Gender Difference on Clinical Outcomes after CRT. / Ando, Kenji; Arita, Takeshi; Goya, Masahiko; Kimura, Takeshi; Shizuta, Satoshi; Isshiki, Takaaki; Nobuyoshi, Masakiyo.

In: journal of arrhythmia, Vol. 27, No. 4, 01.01.2011.

Research output: Contribution to journalArticle

Ando, K, Arita, T, Goya, M, Kimura, T, Shizuta, S, Isshiki, T & Nobuyoshi, M 2011, 'Effect of Gender Difference on Clinical Outcomes after CRT', journal of arrhythmia, vol. 27, no. 4. https://doi.org/10.4020/jhrs.27.OP26_1
Ando K, Arita T, Goya M, Kimura T, Shizuta S, Isshiki T et al. Effect of Gender Difference on Clinical Outcomes after CRT. journal of arrhythmia. 2011 Jan 1;27(4). https://doi.org/10.4020/jhrs.27.OP26_1
Ando, Kenji ; Arita, Takeshi ; Goya, Masahiko ; Kimura, Takeshi ; Shizuta, Satoshi ; Isshiki, Takaaki ; Nobuyoshi, Masakiyo. / Effect of Gender Difference on Clinical Outcomes after CRT. In: journal of arrhythmia. 2011 ; Vol. 27, No. 4.
@article{cf6c3f35b78f4087a9fcbd831aa1e536,
title = "Effect of Gender Difference on Clinical Outcomes after CRT",
abstract = "Background: Female is reported to be preferred CRT compared to male. However, precise effect of gender difference on clinical outcomes is not well known. Methods: We investigated 651 patients from CUBIC study and divided into two groups, 197 female (F group), 454 male (M group). Results: Mean follow up were 22+/15 months. F group was older (71 years vs. 68 years, p=0.01) and more likely to have wide QRS (155 ms vs. 148 ms, p=0.027) and non-ischemic etiology (83{\%} vs. 62{\%}, p<0.0001). M group was more likely to have diabetic (39{\%} vs. 20{\%}, p<0.0001), renal failure (32{\%} vs. 17{\%}, p<0.0001), AF (33{\%} vs. 25{\%}, p=0.036), VT/VF (19{\%} vs. 12{\%}, p=0.027) and larger LV (64mm vs. 60mm, p<0.0001). CRT-D were more common in M group (65{\%} vs. 47{\%}, p<0.0001). NYHA class (F group: 2.9 vs. M group: 2.9) and LVEF (F group: 29{\%} vs. M group: 28{\%}) were similar. There was no difference in NYHA class (2.0 vs. 2.2, p=ns) and responder rate (63{\%} vs.62{\%}, p=ns) at 6-month. The event free survival rates from combined death and heart failure hospitalization, ventricular arrhythmic events were significantly higher in F group (71 {\%} vs.60{\%} at 2-year, Log-rank p=0.038, 79{\%} vs.67{\%} at 2-year, Log-rank p=0.001, respectively). Conclusion: Female has fewer commodities and seems to have preferable clinical outcomes after CRT.",
author = "Kenji Ando and Takeshi Arita and Masahiko Goya and Takeshi Kimura and Satoshi Shizuta and Takaaki Isshiki and Masakiyo Nobuyoshi",
year = "2011",
month = "1",
day = "1",
doi = "10.4020/jhrs.27.OP26_1",
language = "English",
volume = "27",
journal = "Journal of Arrhythmia",
issn = "1880-4276",
publisher = "Elsevier BV",
number = "4",

}

TY - JOUR

T1 - Effect of Gender Difference on Clinical Outcomes after CRT

AU - Ando, Kenji

AU - Arita, Takeshi

AU - Goya, Masahiko

AU - Kimura, Takeshi

AU - Shizuta, Satoshi

AU - Isshiki, Takaaki

AU - Nobuyoshi, Masakiyo

PY - 2011/1/1

Y1 - 2011/1/1

N2 - Background: Female is reported to be preferred CRT compared to male. However, precise effect of gender difference on clinical outcomes is not well known. Methods: We investigated 651 patients from CUBIC study and divided into two groups, 197 female (F group), 454 male (M group). Results: Mean follow up were 22+/15 months. F group was older (71 years vs. 68 years, p=0.01) and more likely to have wide QRS (155 ms vs. 148 ms, p=0.027) and non-ischemic etiology (83% vs. 62%, p<0.0001). M group was more likely to have diabetic (39% vs. 20%, p<0.0001), renal failure (32% vs. 17%, p<0.0001), AF (33% vs. 25%, p=0.036), VT/VF (19% vs. 12%, p=0.027) and larger LV (64mm vs. 60mm, p<0.0001). CRT-D were more common in M group (65% vs. 47%, p<0.0001). NYHA class (F group: 2.9 vs. M group: 2.9) and LVEF (F group: 29% vs. M group: 28%) were similar. There was no difference in NYHA class (2.0 vs. 2.2, p=ns) and responder rate (63% vs.62%, p=ns) at 6-month. The event free survival rates from combined death and heart failure hospitalization, ventricular arrhythmic events were significantly higher in F group (71 % vs.60% at 2-year, Log-rank p=0.038, 79% vs.67% at 2-year, Log-rank p=0.001, respectively). Conclusion: Female has fewer commodities and seems to have preferable clinical outcomes after CRT.

AB - Background: Female is reported to be preferred CRT compared to male. However, precise effect of gender difference on clinical outcomes is not well known. Methods: We investigated 651 patients from CUBIC study and divided into two groups, 197 female (F group), 454 male (M group). Results: Mean follow up were 22+/15 months. F group was older (71 years vs. 68 years, p=0.01) and more likely to have wide QRS (155 ms vs. 148 ms, p=0.027) and non-ischemic etiology (83% vs. 62%, p<0.0001). M group was more likely to have diabetic (39% vs. 20%, p<0.0001), renal failure (32% vs. 17%, p<0.0001), AF (33% vs. 25%, p=0.036), VT/VF (19% vs. 12%, p=0.027) and larger LV (64mm vs. 60mm, p<0.0001). CRT-D were more common in M group (65% vs. 47%, p<0.0001). NYHA class (F group: 2.9 vs. M group: 2.9) and LVEF (F group: 29% vs. M group: 28%) were similar. There was no difference in NYHA class (2.0 vs. 2.2, p=ns) and responder rate (63% vs.62%, p=ns) at 6-month. The event free survival rates from combined death and heart failure hospitalization, ventricular arrhythmic events were significantly higher in F group (71 % vs.60% at 2-year, Log-rank p=0.038, 79% vs.67% at 2-year, Log-rank p=0.001, respectively). Conclusion: Female has fewer commodities and seems to have preferable clinical outcomes after CRT.

UR - http://www.scopus.com/inward/record.url?scp=85009644948&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85009644948&partnerID=8YFLogxK

U2 - 10.4020/jhrs.27.OP26_1

DO - 10.4020/jhrs.27.OP26_1

M3 - Article

VL - 27

JO - Journal of Arrhythmia

JF - Journal of Arrhythmia

SN - 1880-4276

IS - 4

ER -