Effect of nonuniform activity distribution in a porous support on apparent kinetic parameters of a packed-bed immobilized enzyme reactor

Hiromitsu Miyakawa, Fumihide Shiraishi

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The effect of nonuniform activity distribution in a porous support on the apparent kinetic parameters, V̂mapp and K̂mapp, of a packed-bed immobilized enzyme reactor has been theoretically investigated. V̂mapp and K̂maPP increase with the increase of external diffusional resistance, regardless of the type of nonuniform activity distribution. As the external diffusional resistance becomes significant, the apparent kinetic parameters became less dependent on the substrate concentration at the reactor inlet. Like the case of diffusional resistance or electrostatic field, the nonuniform activity distribution had a significant effect on K̂mapp.

Original languageEnglish
Pages (from-to)517-519
Number of pages3
Journalkagaku kogaku ronbunshu
Volume24
Issue number3
DOIs
Publication statusPublished - Jan 1 1998
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)

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