Effect of nonuniform activity distribution in a porous support on apparent kinetic parameters of a packed-bed immobilized enzyme reactor

Hiromitsu Miyakawa, Fumihide Shiraishi

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The effect of nonuniform activity distribution in a porous support on the apparent kinetic parameters, V̂m app and K̂m app, of a packed-bed immobilized enzyme reactor has been theoretically investigated. V̂m app and K̂m aPP increase with the increase of external diffusional resistance, regardless of the type of nonuniform activity distribution. As the external diffusional resistance becomes significant, the apparent kinetic parameters became less dependent on the substrate concentration at the reactor inlet. Like the case of diffusional resistance or electrostatic field, the nonuniform activity distribution had a significant effect on K̂m app.

Original languageEnglish
Pages (from-to)517-519
Number of pages3
Journalkagaku kogaku ronbunshu
Volume24
Issue number3
DOIs
Publication statusPublished - Jan 1 1998
Externally publishedYes

Fingerprint

Immobilized Enzymes
Packed beds
Kinetic parameters
Application programs
Enzymes
Electric fields
Substrates

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

Effect of nonuniform activity distribution in a porous support on apparent kinetic parameters of a packed-bed immobilized enzyme reactor. / Miyakawa, Hiromitsu; Shiraishi, Fumihide.

In: kagaku kogaku ronbunshu, Vol. 24, No. 3, 01.01.1998, p. 517-519.

Research output: Contribution to journalArticle

@article{ed29f9b41faa4b708b62d61a05bdfee8,
title = "Effect of nonuniform activity distribution in a porous support on apparent kinetic parameters of a packed-bed immobilized enzyme reactor",
abstract = "The effect of nonuniform activity distribution in a porous support on the apparent kinetic parameters, V̂m app and K̂m app, of a packed-bed immobilized enzyme reactor has been theoretically investigated. V̂m app and K̂m aPP increase with the increase of external diffusional resistance, regardless of the type of nonuniform activity distribution. As the external diffusional resistance becomes significant, the apparent kinetic parameters became less dependent on the substrate concentration at the reactor inlet. Like the case of diffusional resistance or electrostatic field, the nonuniform activity distribution had a significant effect on K̂m app.",
author = "Hiromitsu Miyakawa and Fumihide Shiraishi",
year = "1998",
month = "1",
day = "1",
doi = "10.1252/kakoronbunshu.24.517",
language = "English",
volume = "24",
pages = "517--519",
journal = "Kagaku Kogaku Ronbunshu",
issn = "0386-216X",
publisher = "The Society of Chemical Engineers, Japan",
number = "3",

}

TY - JOUR

T1 - Effect of nonuniform activity distribution in a porous support on apparent kinetic parameters of a packed-bed immobilized enzyme reactor

AU - Miyakawa, Hiromitsu

AU - Shiraishi, Fumihide

PY - 1998/1/1

Y1 - 1998/1/1

N2 - The effect of nonuniform activity distribution in a porous support on the apparent kinetic parameters, V̂m app and K̂m app, of a packed-bed immobilized enzyme reactor has been theoretically investigated. V̂m app and K̂m aPP increase with the increase of external diffusional resistance, regardless of the type of nonuniform activity distribution. As the external diffusional resistance becomes significant, the apparent kinetic parameters became less dependent on the substrate concentration at the reactor inlet. Like the case of diffusional resistance or electrostatic field, the nonuniform activity distribution had a significant effect on K̂m app.

AB - The effect of nonuniform activity distribution in a porous support on the apparent kinetic parameters, V̂m app and K̂m app, of a packed-bed immobilized enzyme reactor has been theoretically investigated. V̂m app and K̂m aPP increase with the increase of external diffusional resistance, regardless of the type of nonuniform activity distribution. As the external diffusional resistance becomes significant, the apparent kinetic parameters became less dependent on the substrate concentration at the reactor inlet. Like the case of diffusional resistance or electrostatic field, the nonuniform activity distribution had a significant effect on K̂m app.

UR - http://www.scopus.com/inward/record.url?scp=22044457517&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=22044457517&partnerID=8YFLogxK

U2 - 10.1252/kakoronbunshu.24.517

DO - 10.1252/kakoronbunshu.24.517

M3 - Article

AN - SCOPUS:22044457517

VL - 24

SP - 517

EP - 519

JO - Kagaku Kogaku Ronbunshu

JF - Kagaku Kogaku Ronbunshu

SN - 0386-216X

IS - 3

ER -