Abstract
1. 1. Effect of phenylalanine (Phe) on pancreatic amylase secretion in growing chicks was investigated in four experiments. 2. 2. In Experiment 1, birds were injected through a wing vein with 0.25ml Phe at 0, 0.1, 0.5, 2.5 and 12.5mM in physiological saline. No significant difference was observed in amylase secretion among treatments. 3. 3. Effect of various concentrations of Phe with cholecystokinin (CCK, 0.31 Crick unit) on amylase secretion was investigated in Experiment 2. Amylase secretion increased with time, although no significant effect was detected in Phe treatment. 4. 4. Efficacy of Phe and tyrosine (Tyr) injection with CCK on amylase secretion was compared. There was no significant difference between Phe and Tyr treatments. 5. 5. Birds were injected intraperitoneally with dl-p-chlorophenylalanine (p-CP), which is an inhibitor of phenylalanine hydroxylase, or saline 1 day before the collection of pancreatic amylase in Experiment 4. Both chicks showed increased amylase secretion with CCK (0.31 Crick unit), whereas the response was at a drastically reduced rate in chicks with the p-CP treatment.
| Original language | English |
|---|---|
| Pages (from-to) | 531-533 |
| Number of pages | 3 |
| Journal | Comparative Biochemistry and Physiology -- Part A: Physiology |
| Volume | 97 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Jan 1 1990 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Physiology
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Effect of phenylalanine on pancreatic amylase secretion in chicks (Gallus domesticus). / Sung Ik, Yang; Furuse, Mitsuhiro; Nobuhiro, Sugishita; Jun-Ichi, Okumura.
In: Comparative Biochemistry and Physiology -- Part A: Physiology, Vol. 97, No. 4, 01.01.1990, p. 531-533.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effect of phenylalanine on pancreatic amylase secretion in chicks (Gallus domesticus)
AU - Sung Ik, Yang
AU - Furuse, Mitsuhiro
AU - Nobuhiro, Sugishita
AU - Jun-Ichi, Okumura
PY - 1990/1/1
Y1 - 1990/1/1
N2 - 1. 1. Effect of phenylalanine (Phe) on pancreatic amylase secretion in growing chicks was investigated in four experiments. 2. 2. In Experiment 1, birds were injected through a wing vein with 0.25ml Phe at 0, 0.1, 0.5, 2.5 and 12.5mM in physiological saline. No significant difference was observed in amylase secretion among treatments. 3. 3. Effect of various concentrations of Phe with cholecystokinin (CCK, 0.31 Crick unit) on amylase secretion was investigated in Experiment 2. Amylase secretion increased with time, although no significant effect was detected in Phe treatment. 4. 4. Efficacy of Phe and tyrosine (Tyr) injection with CCK on amylase secretion was compared. There was no significant difference between Phe and Tyr treatments. 5. 5. Birds were injected intraperitoneally with dl-p-chlorophenylalanine (p-CP), which is an inhibitor of phenylalanine hydroxylase, or saline 1 day before the collection of pancreatic amylase in Experiment 4. Both chicks showed increased amylase secretion with CCK (0.31 Crick unit), whereas the response was at a drastically reduced rate in chicks with the p-CP treatment.
AB - 1. 1. Effect of phenylalanine (Phe) on pancreatic amylase secretion in growing chicks was investigated in four experiments. 2. 2. In Experiment 1, birds were injected through a wing vein with 0.25ml Phe at 0, 0.1, 0.5, 2.5 and 12.5mM in physiological saline. No significant difference was observed in amylase secretion among treatments. 3. 3. Effect of various concentrations of Phe with cholecystokinin (CCK, 0.31 Crick unit) on amylase secretion was investigated in Experiment 2. Amylase secretion increased with time, although no significant effect was detected in Phe treatment. 4. 4. Efficacy of Phe and tyrosine (Tyr) injection with CCK on amylase secretion was compared. There was no significant difference between Phe and Tyr treatments. 5. 5. Birds were injected intraperitoneally with dl-p-chlorophenylalanine (p-CP), which is an inhibitor of phenylalanine hydroxylase, or saline 1 day before the collection of pancreatic amylase in Experiment 4. Both chicks showed increased amylase secretion with CCK (0.31 Crick unit), whereas the response was at a drastically reduced rate in chicks with the p-CP treatment.
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UR - http://www.scopus.com/inward/citedby.url?scp=0025259977&partnerID=8YFLogxK
U2 - 10.1016/0300-9629(90)90122-9
DO - 10.1016/0300-9629(90)90122-9
M3 - Article
C2 - 1704824
AN - SCOPUS:0025259977
VL - 97
SP - 531
EP - 533
JO - Comparative Biochemistry & Physiology; A: Comparative Physiology
JF - Comparative Biochemistry & Physiology; A: Comparative Physiology
SN - 0300-9629
IS - 4
ER -