Effect of porcine placenta extract supplement on skin condition in healthy adult women: A randomized, double-blind placebo-controlled study

Masumi Nagae, Maki Nagata, Mitsuhiro Teramoto, Masayuki Yamakawa, Takahiro Matsuki, Koichiro Ohnuki, Kuniyoshi Shimizu

Research output: Contribution to journalArticle

Abstract

Placenta extract has been used as a component of ointments for skin dryness and beautification. However, little is known about the effect of oral intake of placenta extract on skin condition. The current study aimed to clinically explore the effect of oral intake of porcine placenta extract on human skin quality. A randomized controlled double-blind trial was performed on healthy women aged 40–59 years (n = 20), who were randomly assigned to receive either placebo or 200 mg of porcine placenta extract once daily for 4 weeks from 28 January 2019 to 25 February 2019. Skin quality parameters and the Simplified Menopausal Index (SMI) were assessed at baseline and after 4 weeks. After 4 weeks, three parameters of skin quality were significantly improved in the porcine placenta group compared with the placebo group. These results suggest that porcine placenta extract can be used as a health food ingredient to maintain humans’ skin condition in the dry winter season.

Original languageEnglish
Article number1671
Pages (from-to)1-12
Number of pages12
JournalNutrients
Volume12
Issue number6
DOIs
Publication statusPublished - Jun 2020

All Science Journal Classification (ASJC) codes

  • Food Science
  • Nutrition and Dietetics

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