Effect of royal jelly on bisphenol A-induced proliferation of human breast cancer cells

Mako Nakaya, Hiroyuki Onda, Kyoko Sasaki, Akiko Yukiyoshi, Hirofumi Tachibana, Koji Yamada

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Royal jelly is known as a functional food containing many useful minerals. In this study, we found an anti-environmental estrogen activity of royal jelly. Bisphenol A (BPA) is an environmental estrogen that stimulates proliferation of human breast cancer MCF-7 cells. Royal jelly inhibited the growth-promoting effect of BPA on MCF-7 cells, even though it did not affect the proliferation of cells in the absence of BPA. In addition, this inhibiting effect of royal jelly was heat-stable.

Original languageEnglish
Pages (from-to)253-255
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Volume71
Issue number1
DOIs
Publication statusPublished - 2007

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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