Effect of Smoking on Oncological Outcome among Prostate Cancer Patients after Radical Prostatectomy with Neoadjuvant Hormonal Therapy

Nobuaki Sato, Masaki Shiota, Ken ichiro Shiga, Eiji Kashiwagi, Ario Takeuchi, Junichi Inokuchi, Akira Yokomizo, Seiji Naito, Masatoshi Eto

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

We analyzed the association between smoking and oncological outcome after radical prostatectomy with neoadjuvant hormonal therapy. This study included men who had undergone radical prostatectomy with neoadjuvant hormonal therapy between 2003 and 2016. We evaluated the association between clinicopathological factors and smoking status as well as the prognostic significance of smoking status in biochemical recurrence. The patients’ backgrounds were comparable between smokers and nonsmokers. Smoking status were identified as significant risk factors of biochemical recurrence. Smoking was a risk factor of biochemical recurrence, suggesting that smoking may promote cancer recurrence after surgical treatment combined with hormonal therapy.

Original languageEnglish
Pages (from-to)559-564
Number of pages6
JournalCancer Investigation
Volume38
Issue number10
DOIs
Publication statusPublished - 2020

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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