[Effect of sympathetic nervous system on circadian rhythm of blood pressure].

Masaaki Nishihara, Yoshitaka Hirooka

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

There is evidence that the abnormal circadian rhythm of blood pressure (BP), such as absent of nocturnal BP fall and exaggerated morning BP surge, assessed by ambulatory BP monitoring is associated with cardiovascular events independent of BP levels in hypertensive patients. The activation of the sympathetic nervous system (SNS) is one of the most important pathophysiological mechanisms underlying abnormalities in circadian BP by affecting cardiac output, salt and volume balance in the kidney, and peripheral vascular resistance. In treating hypertension, especially accompanied by the abnormal circadian rhythm of BP, the effect of antihypertensive drug on SNS activity, as well as the timing of drug administration or the duration of the drug efficacy, should be considered.

Original languageEnglish
Pages (from-to)1374-1378
Number of pages5
JournalNippon rinsho. Japanese journal of clinical medicine
Volume72
Issue number8
Publication statusPublished - 2014
Externally publishedYes

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Sympathetic Nervous System
Circadian Rhythm
Blood Pressure
Vascular Resistance
Cardiac Volume
Ambulatory Blood Pressure Monitoring
Pharmaceutical Preparations
Cardiac Output
Antihypertensive Agents
Salts
Hypertension
Kidney

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

[Effect of sympathetic nervous system on circadian rhythm of blood pressure]. / Nishihara, Masaaki; Hirooka, Yoshitaka.

In: Nippon rinsho. Japanese journal of clinical medicine, Vol. 72, No. 8, 2014, p. 1374-1378.

Research output: Contribution to journalReview article

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