Effect of Vaccinium ashei reade leaves on angiotensin converting enzyme activity in vitro and on systolic blood pressure of spontaneously hypertensive rats in vivo

Hiroshi Sakaida, Koji Nagao, Kouki Higa, Bungo Shirouchi, Nao Inoue, Fumie Hidaka, Takanori Kai, Teruyoshi Yanagita

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The hypotensive effects of Vaccinium ashei reade (blueberry) leaves were studied in vitro and in vivo. Blueberry leaf showed a strong inhibitory effect on angiotensin-converting enzyme activity in vitro. Additionally, feeding of blueberry leaf suppressed the development of essential hypertension in spontaneously hypertensive rats in vivo. These results promise the use of blueberry leaf as a source of dietary hypotensive components.

Original languageEnglish
Pages (from-to)2335-2337
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Volume71
Issue number9
DOIs
Publication statusPublished - Nov 21 2007

Fingerprint

Blueberry Plants
Blood pressure
Enzyme activity
Peptidyl-Dipeptidase A
Inbred SHR Rats
Rats
Blood Pressure
In Vitro Techniques

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

Cite this

Effect of Vaccinium ashei reade leaves on angiotensin converting enzyme activity in vitro and on systolic blood pressure of spontaneously hypertensive rats in vivo. / Sakaida, Hiroshi; Nagao, Koji; Higa, Kouki; Shirouchi, Bungo; Inoue, Nao; Hidaka, Fumie; Kai, Takanori; Yanagita, Teruyoshi.

In: Bioscience, Biotechnology and Biochemistry, Vol. 71, No. 9, 21.11.2007, p. 2335-2337.

Research output: Contribution to journalArticle

Sakaida, Hiroshi ; Nagao, Koji ; Higa, Kouki ; Shirouchi, Bungo ; Inoue, Nao ; Hidaka, Fumie ; Kai, Takanori ; Yanagita, Teruyoshi. / Effect of Vaccinium ashei reade leaves on angiotensin converting enzyme activity in vitro and on systolic blood pressure of spontaneously hypertensive rats in vivo. In: Bioscience, Biotechnology and Biochemistry. 2007 ; Vol. 71, No. 9. pp. 2335-2337.
@article{0a20028f36fd49e6994254247df85d72,
title = "Effect of Vaccinium ashei reade leaves on angiotensin converting enzyme activity in vitro and on systolic blood pressure of spontaneously hypertensive rats in vivo",
abstract = "The hypotensive effects of Vaccinium ashei reade (blueberry) leaves were studied in vitro and in vivo. Blueberry leaf showed a strong inhibitory effect on angiotensin-converting enzyme activity in vitro. Additionally, feeding of blueberry leaf suppressed the development of essential hypertension in spontaneously hypertensive rats in vivo. These results promise the use of blueberry leaf as a source of dietary hypotensive components.",
author = "Hiroshi Sakaida and Koji Nagao and Kouki Higa and Bungo Shirouchi and Nao Inoue and Fumie Hidaka and Takanori Kai and Teruyoshi Yanagita",
year = "2007",
month = "11",
day = "21",
doi = "10.1271/bbb.70277",
language = "English",
volume = "71",
pages = "2335--2337",
journal = "Bioscience, Biotechnology and Biochemistry",
issn = "0916-8451",
publisher = "Japan Society for Bioscience Biotechnology and Agrochemistry",
number = "9",

}

TY - JOUR

T1 - Effect of Vaccinium ashei reade leaves on angiotensin converting enzyme activity in vitro and on systolic blood pressure of spontaneously hypertensive rats in vivo

AU - Sakaida, Hiroshi

AU - Nagao, Koji

AU - Higa, Kouki

AU - Shirouchi, Bungo

AU - Inoue, Nao

AU - Hidaka, Fumie

AU - Kai, Takanori

AU - Yanagita, Teruyoshi

PY - 2007/11/21

Y1 - 2007/11/21

N2 - The hypotensive effects of Vaccinium ashei reade (blueberry) leaves were studied in vitro and in vivo. Blueberry leaf showed a strong inhibitory effect on angiotensin-converting enzyme activity in vitro. Additionally, feeding of blueberry leaf suppressed the development of essential hypertension in spontaneously hypertensive rats in vivo. These results promise the use of blueberry leaf as a source of dietary hypotensive components.

AB - The hypotensive effects of Vaccinium ashei reade (blueberry) leaves were studied in vitro and in vivo. Blueberry leaf showed a strong inhibitory effect on angiotensin-converting enzyme activity in vitro. Additionally, feeding of blueberry leaf suppressed the development of essential hypertension in spontaneously hypertensive rats in vivo. These results promise the use of blueberry leaf as a source of dietary hypotensive components.

UR - http://www.scopus.com/inward/record.url?scp=36148944318&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=36148944318&partnerID=8YFLogxK

U2 - 10.1271/bbb.70277

DO - 10.1271/bbb.70277

M3 - Article

C2 - 17827680

AN - SCOPUS:36148944318

VL - 71

SP - 2335

EP - 2337

JO - Bioscience, Biotechnology and Biochemistry

JF - Bioscience, Biotechnology and Biochemistry

SN - 0916-8451

IS - 9

ER -