Effect of Vaccinium ashei reade leaves on angiotensin converting enzyme activity in vitro and on systolic blood pressure of spontaneously hypertensive rats in vivo

Hiroshi Sakaida, Koji Nagao, Kouki Higa, Bungo Shirouchi, Nao Inoue, Fumie Hidaka, Takanori Kai, Teruyoshi Yanagita

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31 Citations (Scopus)

Abstract

The hypotensive effects of Vaccinium ashei reade (blueberry) leaves were studied in vitro and in vivo. Blueberry leaf showed a strong inhibitory effect on angiotensin-converting enzyme activity in vitro. Additionally, feeding of blueberry leaf suppressed the development of essential hypertension in spontaneously hypertensive rats in vivo. These results promise the use of blueberry leaf as a source of dietary hypotensive components.

Original languageEnglish
Pages (from-to)2335-2337
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Volume71
Issue number9
DOIs
Publication statusPublished - 2007
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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