Abstract
Selective serotonin reuptake inhibitors (SSRIs) are apt to cause gastrointestinal adverse events such as nausea and dyspepsia. Gorei-san (TJ-17), which is composed of five herbs (Alismatis rhizoma, Atractylodis lanceae rhizoma, Polyporus, Hoelen, and Cinnamomi cortex), is a Japanese herbal medicine that has been used to treat nausea, dry mouth, edema, headache, and dizziness. The authors investigated the efficacy of TJ-17 for patients who experienced nausea or dyspepsia induced by SSRIs. Twenty outpatients who experienced nausea or dyspepsia induced by SSRIs were recruited for the study. Seventeen patients were female, three were male, and patient age ranged from 21 to 74 years (49.8 ± 17.0 years). TJ-17 was added to the previous regimen. Nausea and dyspepsia disappeared completely in nine patients, decreased in four patients, decreased slightly in two patients, and did not change in five patients. No adverse events were associated with the addition of TJ-17 in any patient.
| Original language | English |
|---|---|
| Pages (from-to) | 112-114 |
| Number of pages | 3 |
| Journal | Clinical Neuropharmacology |
| Volume | 26 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - May 1 2003 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Pharmacology
- Clinical Neurology
- Pharmacology (medical)
Cite this
Effectiveness of Gorei-san (TJ-17) for treatment of SSRI-induced nausea and dyspepsia : Preliminary observations. / Yamada, Kazuo; Yagi, Gohei; Kanba, Shigenobu.
In: Clinical Neuropharmacology, Vol. 26, No. 3, 01.05.2003, p. 112-114.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effectiveness of Gorei-san (TJ-17) for treatment of SSRI-induced nausea and dyspepsia
T2 - Preliminary observations
AU - Yamada, Kazuo
AU - Yagi, Gohei
AU - Kanba, Shigenobu
PY - 2003/5/1
Y1 - 2003/5/1
N2 - Selective serotonin reuptake inhibitors (SSRIs) are apt to cause gastrointestinal adverse events such as nausea and dyspepsia. Gorei-san (TJ-17), which is composed of five herbs (Alismatis rhizoma, Atractylodis lanceae rhizoma, Polyporus, Hoelen, and Cinnamomi cortex), is a Japanese herbal medicine that has been used to treat nausea, dry mouth, edema, headache, and dizziness. The authors investigated the efficacy of TJ-17 for patients who experienced nausea or dyspepsia induced by SSRIs. Twenty outpatients who experienced nausea or dyspepsia induced by SSRIs were recruited for the study. Seventeen patients were female, three were male, and patient age ranged from 21 to 74 years (49.8 ± 17.0 years). TJ-17 was added to the previous regimen. Nausea and dyspepsia disappeared completely in nine patients, decreased in four patients, decreased slightly in two patients, and did not change in five patients. No adverse events were associated with the addition of TJ-17 in any patient.
AB - Selective serotonin reuptake inhibitors (SSRIs) are apt to cause gastrointestinal adverse events such as nausea and dyspepsia. Gorei-san (TJ-17), which is composed of five herbs (Alismatis rhizoma, Atractylodis lanceae rhizoma, Polyporus, Hoelen, and Cinnamomi cortex), is a Japanese herbal medicine that has been used to treat nausea, dry mouth, edema, headache, and dizziness. The authors investigated the efficacy of TJ-17 for patients who experienced nausea or dyspepsia induced by SSRIs. Twenty outpatients who experienced nausea or dyspepsia induced by SSRIs were recruited for the study. Seventeen patients were female, three were male, and patient age ranged from 21 to 74 years (49.8 ± 17.0 years). TJ-17 was added to the previous regimen. Nausea and dyspepsia disappeared completely in nine patients, decreased in four patients, decreased slightly in two patients, and did not change in five patients. No adverse events were associated with the addition of TJ-17 in any patient.
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UR - http://www.scopus.com/inward/citedby.url?scp=0038051869&partnerID=8YFLogxK
U2 - 10.1097/00002826-200305000-00002
DO - 10.1097/00002826-200305000-00002
M3 - Article
C2 - 12782911
AN - SCOPUS:0038051869
VL - 26
SP - 112
EP - 114
JO - Clinical Neuropharmacology
JF - Clinical Neuropharmacology
SN - 0362-5664
IS - 3
ER -