Effectiveness of ropivacaine and fentanyl for postoperative epidural analgesia following thoracic surgery

Asaha Suzuki, Satoru Osawa, Akifumi Kanai, Akiko Ozawa, Hirotsugu Okamoto, Sumio Hoka

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: Epidural ropivacaine is now a common drug used for postoperative analgesia. However, little information is available concerning regression of sensory blockade and analgesia following prolonged epidural infusion of ropivacaine. We investigated the efficacy of ropivacaine and fentanyl for postoperative analgesia after thoracic surgery. Methods: Thirty patients undergoing thoracic surgery were enrolled. After surgery with general and thoracic epidural anesthesia, continuous epidural infusion of 0.2% ropivacaine+fentanyl (1.67 μg·ml-1) was started at a rate of 6 ml · h-1 for patients whose height was more than 155 cm and 4 ml·h-1 for those below 155 cm with possibility of an additional bolus injection of 3 ml at least every 60 min. Results: An additional epidural injection of 3 ml produced a decrease in VAS without significant changes of vital signs. The greatest VAS was 10± 25 mm in the incision site and 36±38 mm in the ipsilateral shoulder. Sensory blockade was sustained until the morning after the day of surgery. Also blood pressure and heart rate were stable throughout the observation period. There were no adverse effects except for slight nausea in three patients. Conclusions: A bolus of 3 ml with continuous 4-6 ml·h-1 epidural injection of ropivacaine plus a small dose of fentanyl would decrease postoperative pain with stable vital signs in patients after thoracic surgery.

Original languageEnglish
Pages (from-to)2-7
Number of pages6
JournalJapanese Journal of Anesthesiology
Volume54
Issue number1
Publication statusPublished - Jan 1 2005

Fingerprint

Epidural Analgesia
Fentanyl
Thoracic Surgery
Analgesia
Epidural Injections
Vital Signs
Epidural Anesthesia
Postoperative Pain
Ambulatory Surgical Procedures
Nausea
Heart Rate
Observation
ropivacaine
Blood Pressure
Injections
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Anesthesiology and Pain Medicine

Cite this

Suzuki, A., Osawa, S., Kanai, A., Ozawa, A., Okamoto, H., & Hoka, S. (2005). Effectiveness of ropivacaine and fentanyl for postoperative epidural analgesia following thoracic surgery. Japanese Journal of Anesthesiology, 54(1), 2-7.

Effectiveness of ropivacaine and fentanyl for postoperative epidural analgesia following thoracic surgery. / Suzuki, Asaha; Osawa, Satoru; Kanai, Akifumi; Ozawa, Akiko; Okamoto, Hirotsugu; Hoka, Sumio.

In: Japanese Journal of Anesthesiology, Vol. 54, No. 1, 01.01.2005, p. 2-7.

Research output: Contribution to journalArticle

Suzuki, A, Osawa, S, Kanai, A, Ozawa, A, Okamoto, H & Hoka, S 2005, 'Effectiveness of ropivacaine and fentanyl for postoperative epidural analgesia following thoracic surgery', Japanese Journal of Anesthesiology, vol. 54, no. 1, pp. 2-7.
Suzuki, Asaha ; Osawa, Satoru ; Kanai, Akifumi ; Ozawa, Akiko ; Okamoto, Hirotsugu ; Hoka, Sumio. / Effectiveness of ropivacaine and fentanyl for postoperative epidural analgesia following thoracic surgery. In: Japanese Journal of Anesthesiology. 2005 ; Vol. 54, No. 1. pp. 2-7.
@article{a0a66b54922e4f50949c13e5154746f3,
title = "Effectiveness of ropivacaine and fentanyl for postoperative epidural analgesia following thoracic surgery",
abstract = "Background: Epidural ropivacaine is now a common drug used for postoperative analgesia. However, little information is available concerning regression of sensory blockade and analgesia following prolonged epidural infusion of ropivacaine. We investigated the efficacy of ropivacaine and fentanyl for postoperative analgesia after thoracic surgery. Methods: Thirty patients undergoing thoracic surgery were enrolled. After surgery with general and thoracic epidural anesthesia, continuous epidural infusion of 0.2{\%} ropivacaine+fentanyl (1.67 μg·ml-1) was started at a rate of 6 ml · h-1 for patients whose height was more than 155 cm and 4 ml·h-1 for those below 155 cm with possibility of an additional bolus injection of 3 ml at least every 60 min. Results: An additional epidural injection of 3 ml produced a decrease in VAS without significant changes of vital signs. The greatest VAS was 10± 25 mm in the incision site and 36±38 mm in the ipsilateral shoulder. Sensory blockade was sustained until the morning after the day of surgery. Also blood pressure and heart rate were stable throughout the observation period. There were no adverse effects except for slight nausea in three patients. Conclusions: A bolus of 3 ml with continuous 4-6 ml·h-1 epidural injection of ropivacaine plus a small dose of fentanyl would decrease postoperative pain with stable vital signs in patients after thoracic surgery.",
author = "Asaha Suzuki and Satoru Osawa and Akifumi Kanai and Akiko Ozawa and Hirotsugu Okamoto and Sumio Hoka",
year = "2005",
month = "1",
day = "1",
language = "English",
volume = "54",
pages = "2--7",
journal = "Japanese Journal of Anesthesiology",
issn = "0021-4892",
publisher = "Kokuseido Publishing Co. Ltd",
number = "1",

}

TY - JOUR

T1 - Effectiveness of ropivacaine and fentanyl for postoperative epidural analgesia following thoracic surgery

AU - Suzuki, Asaha

AU - Osawa, Satoru

AU - Kanai, Akifumi

AU - Ozawa, Akiko

AU - Okamoto, Hirotsugu

AU - Hoka, Sumio

PY - 2005/1/1

Y1 - 2005/1/1

N2 - Background: Epidural ropivacaine is now a common drug used for postoperative analgesia. However, little information is available concerning regression of sensory blockade and analgesia following prolonged epidural infusion of ropivacaine. We investigated the efficacy of ropivacaine and fentanyl for postoperative analgesia after thoracic surgery. Methods: Thirty patients undergoing thoracic surgery were enrolled. After surgery with general and thoracic epidural anesthesia, continuous epidural infusion of 0.2% ropivacaine+fentanyl (1.67 μg·ml-1) was started at a rate of 6 ml · h-1 for patients whose height was more than 155 cm and 4 ml·h-1 for those below 155 cm with possibility of an additional bolus injection of 3 ml at least every 60 min. Results: An additional epidural injection of 3 ml produced a decrease in VAS without significant changes of vital signs. The greatest VAS was 10± 25 mm in the incision site and 36±38 mm in the ipsilateral shoulder. Sensory blockade was sustained until the morning after the day of surgery. Also blood pressure and heart rate were stable throughout the observation period. There were no adverse effects except for slight nausea in three patients. Conclusions: A bolus of 3 ml with continuous 4-6 ml·h-1 epidural injection of ropivacaine plus a small dose of fentanyl would decrease postoperative pain with stable vital signs in patients after thoracic surgery.

AB - Background: Epidural ropivacaine is now a common drug used for postoperative analgesia. However, little information is available concerning regression of sensory blockade and analgesia following prolonged epidural infusion of ropivacaine. We investigated the efficacy of ropivacaine and fentanyl for postoperative analgesia after thoracic surgery. Methods: Thirty patients undergoing thoracic surgery were enrolled. After surgery with general and thoracic epidural anesthesia, continuous epidural infusion of 0.2% ropivacaine+fentanyl (1.67 μg·ml-1) was started at a rate of 6 ml · h-1 for patients whose height was more than 155 cm and 4 ml·h-1 for those below 155 cm with possibility of an additional bolus injection of 3 ml at least every 60 min. Results: An additional epidural injection of 3 ml produced a decrease in VAS without significant changes of vital signs. The greatest VAS was 10± 25 mm in the incision site and 36±38 mm in the ipsilateral shoulder. Sensory blockade was sustained until the morning after the day of surgery. Also blood pressure and heart rate were stable throughout the observation period. There were no adverse effects except for slight nausea in three patients. Conclusions: A bolus of 3 ml with continuous 4-6 ml·h-1 epidural injection of ropivacaine plus a small dose of fentanyl would decrease postoperative pain with stable vital signs in patients after thoracic surgery.

UR - http://www.scopus.com/inward/record.url?scp=13544253394&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=13544253394&partnerID=8YFLogxK

M3 - Article

C2 - 15717459

AN - SCOPUS:13544253394

VL - 54

SP - 2

EP - 7

JO - Japanese Journal of Anesthesiology

JF - Japanese Journal of Anesthesiology

SN - 0021-4892

IS - 1

ER -