Effects of a novel tungsten-impregnated rubber neck shield on the quality of cerebral images acquired using 15O-labeled gas

Kei Wagatsuma, Keiichi Oda, Kenta Miwa, Motoki Inaji, Muneyuki Sakata, Jun Toyohara, Kiichi Ishiwata, Masayuki Sasaki, Kenji Ishii

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The present study aimed to validate the effects of a novel tungsten-impregnated rubber neck shield on the quality of phantom and clinical 15O-labeled gas positron emission tomography (PET) images. Images were acquired in the presence or absence of a neck shield from a cylindrical phantom containing [15O]H2O (phantom study) and from three individuals using [15O]CO2, [15O]O2 and [15O]CO gas (clinical study). Data were acquired in three-dimensional (3D) mode using a Discovery PET/CT 710. Values for cerebral blood flow, cerebral blood volume, oxygen extraction fraction, and cerebral metabolic rate of oxygen with and without the neck shield were calculated from 15O-labeled gas images. Arterial radioactivity and count characteristics were evaluated in the phantom and clinical studies. The coefficient of variance (CV) for the phantom study and the standard deviation (SD) for functional images were also analyzed. The neck shield decreased the random count rates by 25–59% in the phantom and clinical studies. The noise equivalent count rate (NECR) increased by 44–66% in the phantom and clinical studies. Random count rates and NECR in [15O]CO2 images significantly differed with and without the neck shield. The improvement in visual and physical image quality with the neck shield was not observed in the phantom and clinical studies. The novel neck shield reduced random count rate and improved NECR in a 3D PET study using 15O-labeled gas. The image quality with the neck shield was similar to that without the neck shield.

Original languageEnglish
Pages (from-to)422-430
Number of pages9
JournalRadiological physics and technology
Volume10
Issue number4
DOIs
Publication statusPublished - Dec 1 2017

Fingerprint

Tungsten
Rubber
rubber
tungsten
Neck
Gases
gases
Positron-Emission Tomography
Noise
positrons
tomography
Cerebrovascular Circulation
Oxygen
blood volume
oxygen
Carbon Monoxide
blood flow
radioactivity
Radioactivity
standard deviation

All Science Journal Classification (ASJC) codes

  • Radiation
  • Physical Therapy, Sports Therapy and Rehabilitation
  • Radiology Nuclear Medicine and imaging

Cite this

Effects of a novel tungsten-impregnated rubber neck shield on the quality of cerebral images acquired using 15O-labeled gas. / Wagatsuma, Kei; Oda, Keiichi; Miwa, Kenta; Inaji, Motoki; Sakata, Muneyuki; Toyohara, Jun; Ishiwata, Kiichi; Sasaki, Masayuki; Ishii, Kenji.

In: Radiological physics and technology, Vol. 10, No. 4, 01.12.2017, p. 422-430.

Research output: Contribution to journalArticle

Wagatsuma, Kei ; Oda, Keiichi ; Miwa, Kenta ; Inaji, Motoki ; Sakata, Muneyuki ; Toyohara, Jun ; Ishiwata, Kiichi ; Sasaki, Masayuki ; Ishii, Kenji. / Effects of a novel tungsten-impregnated rubber neck shield on the quality of cerebral images acquired using 15O-labeled gas. In: Radiological physics and technology. 2017 ; Vol. 10, No. 4. pp. 422-430.
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