Effects of added ZnTCP on mechanical and biological properties of apatite cement

Kunio Ishikawa, Y. Miyamoto, T. Toh, T. Yuasa, A. Ito, M. Nagayama, K. Suzuki

Research output: Contribution to journalArticle

Abstract

Effects of added Zn doped β-tricalcium phosphate (ZnTCP) on mechanical and biological properties of apatite cement (AC) was studied. Powder x-ray diffractometer revealed that ZnTCP shows no reactivity with AC. The mechanical strength of AC decreased increasing amounts of added ZnTCP. We observed no effect on the setting time of AC when the amount of ZnTCP was 10% or less. Proliferation of the osteoblastic cells was significantly increased on the surface of AC containing 5% ZnTCP when compared with that containing no ZnTCP. In contrast, proliferation of the cells decreased on the surface of AC containing 10% ZnTCP when compared with that free from ZnTCP; indicating cytotoxity. We concluded therefore, that addition of ZnTCP to AC might be useful to enhance the osteoconductivity of AC when release of Zn2+ can be carefully regulated.

Original languageEnglish
Pages (from-to)785-788
Number of pages4
JournalKey Engineering Materials
Volume192-195
Publication statusPublished - 2001
Externally publishedYes

Fingerprint

Apatites
Apatite
Cements
Phosphates
tricalcium phosphate
Diffractometers
Powders
Strength of materials
X rays

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Ceramics and Composites

Cite this

Ishikawa, K., Miyamoto, Y., Toh, T., Yuasa, T., Ito, A., Nagayama, M., & Suzuki, K. (2001). Effects of added ZnTCP on mechanical and biological properties of apatite cement. Key Engineering Materials, 192-195, 785-788.

Effects of added ZnTCP on mechanical and biological properties of apatite cement. / Ishikawa, Kunio; Miyamoto, Y.; Toh, T.; Yuasa, T.; Ito, A.; Nagayama, M.; Suzuki, K.

In: Key Engineering Materials, Vol. 192-195, 2001, p. 785-788.

Research output: Contribution to journalArticle

Ishikawa, K, Miyamoto, Y, Toh, T, Yuasa, T, Ito, A, Nagayama, M & Suzuki, K 2001, 'Effects of added ZnTCP on mechanical and biological properties of apatite cement', Key Engineering Materials, vol. 192-195, pp. 785-788.
Ishikawa K, Miyamoto Y, Toh T, Yuasa T, Ito A, Nagayama M et al. Effects of added ZnTCP on mechanical and biological properties of apatite cement. Key Engineering Materials. 2001;192-195:785-788.
Ishikawa, Kunio ; Miyamoto, Y. ; Toh, T. ; Yuasa, T. ; Ito, A. ; Nagayama, M. ; Suzuki, K. / Effects of added ZnTCP on mechanical and biological properties of apatite cement. In: Key Engineering Materials. 2001 ; Vol. 192-195. pp. 785-788.
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AU - Nagayama, M.

AU - Suzuki, K.

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