Effects of hypothalamic lesions on active sodium-potassium transport in the extensor digitorum longus muscles of hypokalemic rat

T. Katafuchi, H. Yoshimatsu, Y. Oomura, N. Akaike

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The CNS-induced suppression on muscle Na+-K+ pump was studied in "twitch" muscle, extensor digitorum longus (EDL), of hypokalemic rats which were fed a K+ deficient diet for several weeks. Peripheral nerve section or bilateral lesion of the ventromedial hypothalamic nucleus had no effect on the Na+ and K+ contents in EDL of hypokalemic rats. However, lesions of the paraventricular nucleus caused the net Na+ loss and the net K+ uptake in the muscles. Lesions in either the dorsomedial nucleus or anterior hypothalamus also caused significant net K+ uptake but the net Na+ loss was not significant. The results were compared with those of "tonic" muscle, soleus, reported previously.

Original languageEnglish
Pages (from-to)151-153
Number of pages3
JournalBrain Research Bulletin
Volume17
Issue number2
DOIs
Publication statusPublished - Aug 1986

Fingerprint

Potassium
Sodium
Muscles
Anterior Hypothalamic Nucleus
Ventromedial Hypothalamic Nucleus
Mediodorsal Thalamic Nucleus
Paraventricular Hypothalamic Nucleus
Peripheral Nerves
Skeletal Muscle
Diet

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Cite this

Effects of hypothalamic lesions on active sodium-potassium transport in the extensor digitorum longus muscles of hypokalemic rat. / Katafuchi, T.; Yoshimatsu, H.; Oomura, Y.; Akaike, N.

In: Brain Research Bulletin, Vol. 17, No. 2, 08.1986, p. 151-153.

Research output: Contribution to journalArticle

Katafuchi, T. ; Yoshimatsu, H. ; Oomura, Y. ; Akaike, N. / Effects of hypothalamic lesions on active sodium-potassium transport in the extensor digitorum longus muscles of hypokalemic rat. In: Brain Research Bulletin. 1986 ; Vol. 17, No. 2. pp. 151-153.
@article{37b80cc507b9406ab20d151a2016d1cc,
title = "Effects of hypothalamic lesions on active sodium-potassium transport in the extensor digitorum longus muscles of hypokalemic rat",
abstract = "The CNS-induced suppression on muscle Na+-K+ pump was studied in {"}twitch{"} muscle, extensor digitorum longus (EDL), of hypokalemic rats which were fed a K+ deficient diet for several weeks. Peripheral nerve section or bilateral lesion of the ventromedial hypothalamic nucleus had no effect on the Na+ and K+ contents in EDL of hypokalemic rats. However, lesions of the paraventricular nucleus caused the net Na+ loss and the net K+ uptake in the muscles. Lesions in either the dorsomedial nucleus or anterior hypothalamus also caused significant net K+ uptake but the net Na+ loss was not significant. The results were compared with those of {"}tonic{"} muscle, soleus, reported previously.",
author = "T. Katafuchi and H. Yoshimatsu and Y. Oomura and N. Akaike",
year = "1986",
month = "8",
doi = "10.1016/0361-9230(86)90110-3",
language = "English",
volume = "17",
pages = "151--153",
journal = "Brain Research Bulletin",
issn = "0361-9230",
publisher = "Elsevier Inc.",
number = "2",

}

TY - JOUR

T1 - Effects of hypothalamic lesions on active sodium-potassium transport in the extensor digitorum longus muscles of hypokalemic rat

AU - Katafuchi, T.

AU - Yoshimatsu, H.

AU - Oomura, Y.

AU - Akaike, N.

PY - 1986/8

Y1 - 1986/8

N2 - The CNS-induced suppression on muscle Na+-K+ pump was studied in "twitch" muscle, extensor digitorum longus (EDL), of hypokalemic rats which were fed a K+ deficient diet for several weeks. Peripheral nerve section or bilateral lesion of the ventromedial hypothalamic nucleus had no effect on the Na+ and K+ contents in EDL of hypokalemic rats. However, lesions of the paraventricular nucleus caused the net Na+ loss and the net K+ uptake in the muscles. Lesions in either the dorsomedial nucleus or anterior hypothalamus also caused significant net K+ uptake but the net Na+ loss was not significant. The results were compared with those of "tonic" muscle, soleus, reported previously.

AB - The CNS-induced suppression on muscle Na+-K+ pump was studied in "twitch" muscle, extensor digitorum longus (EDL), of hypokalemic rats which were fed a K+ deficient diet for several weeks. Peripheral nerve section or bilateral lesion of the ventromedial hypothalamic nucleus had no effect on the Na+ and K+ contents in EDL of hypokalemic rats. However, lesions of the paraventricular nucleus caused the net Na+ loss and the net K+ uptake in the muscles. Lesions in either the dorsomedial nucleus or anterior hypothalamus also caused significant net K+ uptake but the net Na+ loss was not significant. The results were compared with those of "tonic" muscle, soleus, reported previously.

UR - http://www.scopus.com/inward/record.url?scp=0022539122&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022539122&partnerID=8YFLogxK

U2 - 10.1016/0361-9230(86)90110-3

DO - 10.1016/0361-9230(86)90110-3

M3 - Article

C2 - 3021289

AN - SCOPUS:0022539122

VL - 17

SP - 151

EP - 153

JO - Brain Research Bulletin

JF - Brain Research Bulletin

SN - 0361-9230

IS - 2

ER -