Effects of hypothalamic lesions on active sodium-potassium transport in the extensor digitorum longus muscles of hypokalemic rat

T. Katafuchi, H. Yoshimatsu, Y. Oomura, N. Akaike

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The CNS-induced suppression on muscle Na+-K+ pump was studied in "twitch" muscle, extensor digitorum longus (EDL), of hypokalemic rats which were fed a K+ deficient diet for several weeks. Peripheral nerve section or bilateral lesion of the ventromedial hypothalamic nucleus had no effect on the Na+ and K+ contents in EDL of hypokalemic rats. However, lesions of the paraventricular nucleus caused the net Na+ loss and the net K+ uptake in the muscles. Lesions in either the dorsomedial nucleus or anterior hypothalamus also caused significant net K+ uptake but the net Na+ loss was not significant. The results were compared with those of "tonic" muscle, soleus, reported previously.

Original languageEnglish
Pages (from-to)151-153
Number of pages3
JournalBrain Research Bulletin
Volume17
Issue number2
DOIs
Publication statusPublished - Aug 1986

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

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