Effects of milk fermented by Lactobacillus gasseri SBT2055 on adipocyte size in rats

Masao Sato, Kazunori Uzu, Takeshi Yoshida, Essam M. Hamad, Hiroshi Kawakami, Hiroaki Matsuyama, Ibrahim A. Abd El-Gawad, Katsumi Imaizumi

Research output: Contribution to journalArticle

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Abstract

Despite adequate scientific evidence of the potential benefits of probiotics to human health or disease prevention, their contribution to the growth of adipose tissue remains to be established. Four-week-old male Sprague-Dawley rats were fed a diet containing skim milk (control diet) or skim milk fermented by Lactobacillus gasseri SBT2055 (LGSP diet) for 4 weeks. Their body weight gain, adipose tissue weight, adipocyte size distribution profile, blood and hepatic lipids, and serum leptin, glucose and adiponectin levels were determined. There was a significant reduction in average adipocyte size in mesenteric white adipose tissue (P = 0.004). Moreover, the rats fed the LGSP diet displayed greater numbers of small adipocytes from mesenteric and retroperitoneal adipose tissues than did those on the control diet. Whereas adiponectin concentrations did not differ between the groups, serum leptin concentrations were decreased to 32 % in the LGSP diet group compared with the control group. Concentrations of serum glucose and lipids, and liver lipids, except for the liver TAG level, were similar in the two groups. These results indicate a possible role for a fermented milk product in the regulation of adipose tissue growth.

Original languageEnglish
Pages (from-to)1013-1017
Number of pages5
JournalBritish Journal of Nutrition
Volume99
Issue number5
DOIs
Publication statusPublished - Oct 7 2008

Fingerprint

Adipocytes
Milk
Diet
Adipose Tissue
Adiponectin
Leptin
Lipids
Liver
Serum
Cultured Milk Products
Glucose
White Adipose Tissue
Intra-Abdominal Fat
Probiotics
Growth
Weight Gain
Sprague Dawley Rats
Lactobacillus gasseri
Body Weight
Weights and Measures

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Sato, M., Uzu, K., Yoshida, T., Hamad, E. M., Kawakami, H., Matsuyama, H., ... Imaizumi, K. (2008). Effects of milk fermented by Lactobacillus gasseri SBT2055 on adipocyte size in rats. British Journal of Nutrition, 99(5), 1013-1017. https://doi.org/10.1017/S0007114507839006

Effects of milk fermented by Lactobacillus gasseri SBT2055 on adipocyte size in rats. / Sato, Masao; Uzu, Kazunori; Yoshida, Takeshi; Hamad, Essam M.; Kawakami, Hiroshi; Matsuyama, Hiroaki; Abd El-Gawad, Ibrahim A.; Imaizumi, Katsumi.

In: British Journal of Nutrition, Vol. 99, No. 5, 07.10.2008, p. 1013-1017.

Research output: Contribution to journalArticle

Sato, M, Uzu, K, Yoshida, T, Hamad, EM, Kawakami, H, Matsuyama, H, Abd El-Gawad, IA & Imaizumi, K 2008, 'Effects of milk fermented by Lactobacillus gasseri SBT2055 on adipocyte size in rats', British Journal of Nutrition, vol. 99, no. 5, pp. 1013-1017. https://doi.org/10.1017/S0007114507839006
Sato, Masao ; Uzu, Kazunori ; Yoshida, Takeshi ; Hamad, Essam M. ; Kawakami, Hiroshi ; Matsuyama, Hiroaki ; Abd El-Gawad, Ibrahim A. ; Imaizumi, Katsumi. / Effects of milk fermented by Lactobacillus gasseri SBT2055 on adipocyte size in rats. In: British Journal of Nutrition. 2008 ; Vol. 99, No. 5. pp. 1013-1017.
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