Effects of oral contraceptive steroids (norethisterone/mestranol) on the activities of hepatic drug-metabolizing enzymes in iron-deficient anemic rats

K. Mizokami, K. Suzuki, Kazuhide Inoue, M. Sunouchi, S. Hirakawa, S. Goto, A. Takanaka, Y. Kanke

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Either oral contraceptive steroid (norethisterone/mestranol; N/M) treatment or iron-deficiency (Fe(-)) anemia alone caused an increase in NADPH cytochrome c reductase and in three hepatic microsomal mixed-function oxidase activities in female rats. When N/M treatment and the Fe(-) diet are combined, no further change in hepatic enzyme activity is seen compared with that with either treatment alone.

Original languageEnglish
Pages (from-to)734-736
Number of pages3
JournalExperientia
Volume41
Issue number6
DOIs
Publication statusPublished - Jun 1 1985

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Mestranol
Norethindrone
NADPH-Ferrihemoprotein Reductase
Enzyme activity
Nutrition
Oral Contraceptives
Mixed Function Oxygenases
Rats
Iron
Steroids
Iron-Deficiency Anemias
Liver
Enzymes
Pharmaceutical Preparations
Diet

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Effects of oral contraceptive steroids (norethisterone/mestranol) on the activities of hepatic drug-metabolizing enzymes in iron-deficient anemic rats. / Mizokami, K.; Suzuki, K.; Inoue, Kazuhide; Sunouchi, M.; Hirakawa, S.; Goto, S.; Takanaka, A.; Kanke, Y.

In: Experientia, Vol. 41, No. 6, 01.06.1985, p. 734-736.

Research output: Contribution to journalArticle

Mizokami, K. ; Suzuki, K. ; Inoue, Kazuhide ; Sunouchi, M. ; Hirakawa, S. ; Goto, S. ; Takanaka, A. ; Kanke, Y. / Effects of oral contraceptive steroids (norethisterone/mestranol) on the activities of hepatic drug-metabolizing enzymes in iron-deficient anemic rats. In: Experientia. 1985 ; Vol. 41, No. 6. pp. 734-736.
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