Effects of probiotic Lactobacillus salivarius WB21 on halitosis and oral health

An open-label pilot trial

Tomoyuki Iwamoto, Nao Suzuki, Kazunari Tanabe, Toru Takeshita, Takao Hirofuji

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Objective: The objective of this study was to evaluate whether oral administration of lactobacilli alters the degree of halitosis and clinical conditions associated with halitosis. Study design: Twenty patients with genuine halitosis were given 2.0 × 109 Lactobacillus salivarius WB21 and xylitol in tablet form daily. Oral malodor and clinical parameters were evaluated at the same time of day for each patient after 2 and 4 weeks. Results: All 20 patients were positive for L. salivarius DNA in their saliva at 2 weeks, although 12 patients were negative for this organism at baseline. Oral malodor parameters significantly decreased at 2 weeks in the subjects with physiologic halitosis. The scores of an organoleptic test and bleeding on probing significantly decreased at 4 weeks in the subjects with oral pathologic halitosis. Conclusions: Oral administration of probiotic lactobacilli primarily improved physiologic halitosis and also showed beneficial effects on bleeding on probing from the periodontal pocket.

Original languageEnglish
Pages (from-to)201-208
Number of pages8
JournalOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology
Volume110
Issue number2
DOIs
Publication statusPublished - Aug 13 2010

Fingerprint

Halitosis
Oral Health
Probiotics
Lactobacillus
Oral Administration
Hemorrhage
Periodontal Pocket
Xylitol
Saliva
Tablets
Lactobacillus salivarius
DNA

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology
  • Surgery
  • Dentistry(all)
  • Oral Surgery

Cite this

Effects of probiotic Lactobacillus salivarius WB21 on halitosis and oral health : An open-label pilot trial. / Iwamoto, Tomoyuki; Suzuki, Nao; Tanabe, Kazunari; Takeshita, Toru; Hirofuji, Takao.

In: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology, Vol. 110, No. 2, 13.08.2010, p. 201-208.

Research output: Contribution to journalArticle

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