Effects of sex, height and age on motor evoked potentials with magnetic stimulation

Shozo Tobimatsu, S. J. Sun, R. Fukui, M. Kato

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Magnetic stimulation of the brain and cervical and lumbar spinal roots was performed on 48 healthy subjects in order to investigate the effects of sex, height and age on motor evoked potentials (MEPs). The compound muscle action potentials were recorded from the abductor pollicis brevis and abductor hallucis muscles. The central motor conduction time (CMCT) was measured between the cerebral cortex and the cervical root and also between the cerebral cortex and the lumbar root. A multiple regression analysis was used to determine which of the physical variables, namely sex, height and age, were significant. A significant gender difference was observed in the MEP latencies and CMCT of the leg, but not in those of the hand. Both height and age had a significant effect on the leg MEP latencies with a lesser effect on the hand MEP latencies, The leg CMCT was also significantly influenced by height and age, while the hand CMCT was not. These results thus suggest that physical variables are very important in defining normal MEPs, especially in the lower limbs. Therefore, when we assess motor function in patients with neurological disorders, both the patients and control groups should be matched for sex, height and age distribution.

Original languageEnglish
Pages (from-to)256-261
Number of pages6
JournalJournal of Neurology
Volume245
Issue number5
DOIs
Publication statusPublished - Jun 2 1998

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Motor Evoked Potentials
Leg
Hand
Cerebral Cortex
Muscles
Sex Distribution
Spinal Nerve Roots
Age Distribution
Nervous System Diseases
Action Potentials
Lower Extremity
Healthy Volunteers
Regression Analysis
Control Groups
Brain

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

Cite this

Effects of sex, height and age on motor evoked potentials with magnetic stimulation. / Tobimatsu, Shozo; Sun, S. J.; Fukui, R.; Kato, M.

In: Journal of Neurology, Vol. 245, No. 5, 02.06.1998, p. 256-261.

Research output: Contribution to journalArticle

Tobimatsu, Shozo ; Sun, S. J. ; Fukui, R. ; Kato, M. / Effects of sex, height and age on motor evoked potentials with magnetic stimulation. In: Journal of Neurology. 1998 ; Vol. 245, No. 5. pp. 256-261.
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