Effects of xylooligosaccharides on blood glucose, serum and liver lipids and-cecum short-chain fatty acids in diabetic rats

Katsumi Imaizumi; Yoriko Nakatsu; Masao Sato; Yasni Sedarnawati; Michihito Sugano

doi:10.1080/00021369.1991.10870553

Effects of xylooligosaccharides on blood glucose, serum and liver lipids and-cecum short-chain fatty acids in diabetic rats

Katsumi Imaizumi, Yoriko Nakatsu, Masao Sato, Yasni Sedarnawati, Michihito Sugano

Food Science and Biotechnology

Research output: Contribution to journal › Article › peer-review

93 Citations (Scopus)

Abstract

The effect of supplementing xylooligosaccharides (XO) to purified diets on growth performance and several metabolic parameters was examined in streptozotocin-induced diabetic rats. The dietary XO improved growth retardation, hyperphagia, polydipsia, elevation of serum glucose, triglyceride and cholesterol, reduction of liver triglyceride, and fatty acid composition (reduction of the desaturation index) of liver phosphatidylcholine. In addition, the XO diet yielded an acidic en-vironment in the cecum by increasing the pool size of acetic acid. Thus, XO, which is half as sweet as sucrose, can be applicable to foods as a sweetener that is capable of improving diabetic symptoms.

Original language	English
Pages (from-to)	199-205
Number of pages	7
Journal	Agricultural and Biological Chemistry
Volume	55
Issue number	1
DOIs	https://doi.org/10.1080/00021369.1991.10870553
Publication status	Published - Jan 1991

All Science Journal Classification (ASJC) codes

Biochemistry, Genetics and Molecular Biology(all)
Agricultural and Biological Sciences(all)

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10.1080/00021369.1991.10870553

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abstract = "The effect of supplementing xylooligosaccharides (XO) to purified diets on growth performance and several metabolic parameters was examined in streptozotocin-induced diabetic rats. The dietary XO improved growth retardation, hyperphagia, polydipsia, elevation of serum glucose, triglyceride and cholesterol, reduction of liver triglyceride, and fatty acid composition (reduction of the desaturation index) of liver phosphatidylcholine. In addition, the XO diet yielded an acidic en-vironment in the cecum by increasing the pool size of acetic acid. Thus, XO, which is half as sweet as sucrose, can be applicable to foods as a sweetener that is capable of improving diabetic symptoms.",

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AU - Imaizumi, Katsumi

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AU - Sedarnawati, Yasni

AU - Sugano, Michihito

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AB - The effect of supplementing xylooligosaccharides (XO) to purified diets on growth performance and several metabolic parameters was examined in streptozotocin-induced diabetic rats. The dietary XO improved growth retardation, hyperphagia, polydipsia, elevation of serum glucose, triglyceride and cholesterol, reduction of liver triglyceride, and fatty acid composition (reduction of the desaturation index) of liver phosphatidylcholine. In addition, the XO diet yielded an acidic en-vironment in the cecum by increasing the pool size of acetic acid. Thus, XO, which is half as sweet as sucrose, can be applicable to foods as a sweetener that is capable of improving diabetic symptoms.

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Effects of xylooligosaccharides on blood glucose, serum and liver lipids and-cecum short-chain fatty acids in diabetic rats

Abstract

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