Effects of xylooligosaccharides on blood glucose, serum and liver lipids and-cecum short-chain fatty acids in diabetic rats

Katsumi Imaizumi, Yoriko Nakatsu, Masao Sato, Yasni Sedarnawati, Michihito Sugano

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The effect of supplementing xylooligosaccharides (XO) to purified diets on growth performance and several metabolic parameters was examined in streptozotocin-induced diabetic rats. The dietary XO improved growth retardation, hyperphagia, polydipsia, elevation of serum glucose, triglyceride and cholesterol, reduction of liver triglyceride, and fatty acid composition (reduction of the desaturation index) of liver phosphatidylcholine. In addition, the XO diet yielded an acidic en-vironment in the cecum by increasing the pool size of acetic acid. Thus, XO, which is half as sweet as sucrose, can be applicable to foods as a sweetener that is capable of improving diabetic symptoms.

Original languageEnglish
Pages (from-to)199-205
Number of pages7
JournalAgricultural and Biological Chemistry
Issue number1
Publication statusPublished - Jan 1991


All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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