Efficacy and timing of gastrografin administration after ileus tube insertion in patients with adhesive small bowel obstruction

Mitsuru Esaki, Yu Tamura, Ryoji Ichijima, Sho Suzuki, Maho Iwamoto, Yosuke Minoda, Mitsuhiko Moriyama, Takuji Gotoda

Research output: Contribution to journalArticlepeer-review


Background and study aims: Gastrografin administration (GA) is performed for adhesive small bowel obstruction (ASBO) in cases when decompression therapy using an ileus tube fails to relieve the obstruction. This study evaluated the efficacy of GA and optimized its timing after ileus tube insertion. Patients and methods: In this retrospective study, we evaluated data from patients with ASBO admitted between January 2014 and August 2018 and included patients who underwent ileus tube intubation and GA. The patients were classified as those treated with GA within 48 h after admission (early GA [EGA]) and those treated later with GA (delayed GA [DGA]). Propensity score matching was performed to compensate for differences between the groups. Short-term outcomes were compared between the two groups. Results: We included 67 and 80 patients in the EGA and DGA groups, respectively, and 55 pairs with similar background characteristics were matched. The rates of successful conservative management were 87.3% (48/55) in the EGA group, 96.4% (53/55) in the DGA group, and 91.8% (101/110) in the entire sample. The median period of ileus tube insertion in the DGA group was significantly lower than that in the EGA group, whereas other outcomes did not significantly differ between the groups. Aspiration pneumonia occurred in one patient in the EGA group. Conclusions: GA with an ileus tube achieved a high rate of successful conservative management. Follow-up using decompression with an ileus tube for at least 48 h after admission is recommended in patients with ASBO.

Original languageEnglish
Pages (from-to)45-51
Number of pages7
JournalArab Journal of Gastroenterology
Issue number1
Publication statusPublished - Feb 2022
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Gastroenterology


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