EGFR gets in the way of microRNA biogenesis

Naohiro Nishida, Koshi Mimori, Masaki Mori, George A. Calin

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Recent studies suggest that microRNA (miRNA) processing is a key regulatory step in the miRNA biogenesis as well as its transcriptional control. In a paper recently published in Nature, Shen et al. revealed that epidermal growth factor receptor (EGFR) directly interacts with argonaute 2 (AGO2), a critical component of RNA-induced silencing complex (RISC), and inhibits the maturation of specific tumor suppressive miRNAs under hypoxic condition.

Original languageEnglish
Pages (from-to)1157-1158
Number of pages2
JournalCell Research
Volume23
Issue number10
DOIs
Publication statusPublished - Oct 1 2013

Fingerprint

MicroRNAs
Epidermal Growth Factor Receptor
RNA-Induced Silencing Complex
Neoplasms

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Cell Biology

Cite this

EGFR gets in the way of microRNA biogenesis. / Nishida, Naohiro; Mimori, Koshi; Mori, Masaki; Calin, George A.

In: Cell Research, Vol. 23, No. 10, 01.10.2013, p. 1157-1158.

Research output: Contribution to journalArticle

Nishida, Naohiro ; Mimori, Koshi ; Mori, Masaki ; Calin, George A. / EGFR gets in the way of microRNA biogenesis. In: Cell Research. 2013 ; Vol. 23, No. 10. pp. 1157-1158.
@article{3738dfc265d442e1aa57069505d962b3,
title = "EGFR gets in the way of microRNA biogenesis",
abstract = "Recent studies suggest that microRNA (miRNA) processing is a key regulatory step in the miRNA biogenesis as well as its transcriptional control. In a paper recently published in Nature, Shen et al. revealed that epidermal growth factor receptor (EGFR) directly interacts with argonaute 2 (AGO2), a critical component of RNA-induced silencing complex (RISC), and inhibits the maturation of specific tumor suppressive miRNAs under hypoxic condition.",
author = "Naohiro Nishida and Koshi Mimori and Masaki Mori and Calin, {George A.}",
year = "2013",
month = "10",
day = "1",
doi = "10.1038/cr.2013.87",
language = "English",
volume = "23",
pages = "1157--1158",
journal = "Cell Research",
issn = "1001-0602",
publisher = "Nature Publishing Group",
number = "10",

}

TY - JOUR

T1 - EGFR gets in the way of microRNA biogenesis

AU - Nishida, Naohiro

AU - Mimori, Koshi

AU - Mori, Masaki

AU - Calin, George A.

PY - 2013/10/1

Y1 - 2013/10/1

N2 - Recent studies suggest that microRNA (miRNA) processing is a key regulatory step in the miRNA biogenesis as well as its transcriptional control. In a paper recently published in Nature, Shen et al. revealed that epidermal growth factor receptor (EGFR) directly interacts with argonaute 2 (AGO2), a critical component of RNA-induced silencing complex (RISC), and inhibits the maturation of specific tumor suppressive miRNAs under hypoxic condition.

AB - Recent studies suggest that microRNA (miRNA) processing is a key regulatory step in the miRNA biogenesis as well as its transcriptional control. In a paper recently published in Nature, Shen et al. revealed that epidermal growth factor receptor (EGFR) directly interacts with argonaute 2 (AGO2), a critical component of RNA-induced silencing complex (RISC), and inhibits the maturation of specific tumor suppressive miRNAs under hypoxic condition.

UR - http://www.scopus.com/inward/record.url?scp=84885189895&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84885189895&partnerID=8YFLogxK

U2 - 10.1038/cr.2013.87

DO - 10.1038/cr.2013.87

M3 - Article

VL - 23

SP - 1157

EP - 1158

JO - Cell Research

JF - Cell Research

SN - 1001-0602

IS - 10

ER -