Electrode Modification by Long-Chain, Dialkyl Disulfide Reagent Haying Terminal Dinitrophenyl Group and Its Application to Impedimetric Immunosensors

Hiroaki Taira; Mizuo Maeda; Makoto Takagi; Koji Nakano

doi:10.2116/analsci.9.199

Electrode Modification by Long-Chain, Dialkyl Disulfide Reagent Haying Terminal Dinitrophenyl Group and Its Application to Impedimetric Immunosensors

Hiroaki Taira, Mizuo Maeda, Makoto Takagi, Koji Nakano

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

Abstract

A long-chain, dialkyl disulfide having a terminal dinitrophenyl (DNP) group was newly synthesized for modification of a surface of gold with chemisorbed, self-assembled organic monolayers. The resulting monolayer was characterized by infrared spectroscopy of reflection absorption spectroscopy mode, by cyclic voltammetric measurement and by electrical impedance measurement. Coupled with impedance measurements, a possible application of the modified electrode system to impedimetric immunosensors was demonstrated. The sensor gave electrical response to anti-DNP antibody at 10 - 103 ng cm'3 concentration.

Original language	English
Pages (from-to)	199-206
Number of pages	8
Journal	analytical sciences
Volume	9
Issue number	2
DOIs	https://doi.org/10.2116/analsci.9.199
Publication status	Published - Jan 1 1993

All Science Journal Classification (ASJC) codes

Analytical Chemistry

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AU - Nakano, Koji

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Electrode Modification by Long-Chain, Dialkyl Disulfide Reagent Haying Terminal Dinitrophenyl Group and Its Application to Impedimetric Immunosensors

Abstract

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