Electrode Modification by Long-Chain, Dialkyl Disulfide Reagent Haying Terminal Dinitrophenyl Group and Its Application to Impedimetric Immunosensors

Hiroaki Taira, Mizuo Maeda, Makoto Takagi, Koji Nakano

    Research output: Contribution to journalArticlepeer-review

    39 Citations (Scopus)

    Abstract

    A long-chain, dialkyl disulfide having a terminal dinitrophenyl (DNP) group was newly synthesized for modification of a surface of gold with chemisorbed, self-assembled organic monolayers. The resulting monolayer was characterized by infrared spectroscopy of reflection absorption spectroscopy mode, by cyclic voltammetric measurement and by electrical impedance measurement. Coupled with impedance measurements, a possible application of the modified electrode system to impedimetric immunosensors was demonstrated. The sensor gave electrical response to anti-DNP antibody at 10 - 103 ng cm'3 concentration.

    Original languageEnglish
    Pages (from-to)199-206
    Number of pages8
    Journalanalytical sciences
    Volume9
    Issue number2
    DOIs
    Publication statusPublished - Jan 1 1993

    All Science Journal Classification (ASJC) codes

    • Analytical Chemistry

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