Electron-tracking Compton camera imaging of technetium-95m

Yuichi Hatsukawa, Takehito Hayakawa, Kazuaki Tsukada, Kazuyuki Hashimoto, Tetsuya Sato, Masato Asai, Atsushi Toyoshima, Toru Tanimori, Shinya Sonoda, Shigeto Kabuki, Hiroyuki Kimura, Atsushi Takada, Tetsuya Mizumoto, Seiya Takaki

Research output: Contribution to journalArticle

Abstract

Imaging was conducted using an electron tracking-Compton camera (ETCC), which measures γ-rays with energies in the range of 200–900 keV from 95m Tc. 95m Tc was produced by the 95 Mo (p, n) 95m Tc reaction on a 95 Mo-enriched target. A method for recycling 95 Mo-enriched molybdenum trioxide was employed, and the recycled yield of 95 Mo was 70%-90%. Images were obtained with the gate of three energies. The results showed that the spatial resolution increases with increasing γ-ray energy, and suggested that the ETCC with high-energy γ-ray emitters such as 95m Tc is useful for the medical imaging of deep tissue and organs in the human body.

Original languageEnglish
Article numbere0208909
JournalPloS one
Volume13
Issue number12
DOIs
Publication statusPublished - Dec 2018

Fingerprint

technetium
Technetium
cameras
Cameras
electrons
image analysis
Electrons
Imaging techniques
energy
Medical imaging
Recycling
Diagnostic Imaging
Human Body
Tissue
emitters (equipment)
molybdenum
recycling
molybdenum trioxide

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • General

Cite this

Hatsukawa, Y., Hayakawa, T., Tsukada, K., Hashimoto, K., Sato, T., Asai, M., ... Takaki, S. (2018). Electron-tracking Compton camera imaging of technetium-95m. PloS one, 13(12), [e0208909]. https://doi.org/10.1371/journal.pone.0208909

Electron-tracking Compton camera imaging of technetium-95m. / Hatsukawa, Yuichi; Hayakawa, Takehito; Tsukada, Kazuaki; Hashimoto, Kazuyuki; Sato, Tetsuya; Asai, Masato; Toyoshima, Atsushi; Tanimori, Toru; Sonoda, Shinya; Kabuki, Shigeto; Kimura, Hiroyuki; Takada, Atsushi; Mizumoto, Tetsuya; Takaki, Seiya.

In: PloS one, Vol. 13, No. 12, e0208909, 12.2018.

Research output: Contribution to journalArticle

Hatsukawa, Y, Hayakawa, T, Tsukada, K, Hashimoto, K, Sato, T, Asai, M, Toyoshima, A, Tanimori, T, Sonoda, S, Kabuki, S, Kimura, H, Takada, A, Mizumoto, T & Takaki, S 2018, 'Electron-tracking Compton camera imaging of technetium-95m', PloS one, vol. 13, no. 12, e0208909. https://doi.org/10.1371/journal.pone.0208909
Hatsukawa Y, Hayakawa T, Tsukada K, Hashimoto K, Sato T, Asai M et al. Electron-tracking Compton camera imaging of technetium-95m. PloS one. 2018 Dec;13(12). e0208909. https://doi.org/10.1371/journal.pone.0208909
Hatsukawa, Yuichi ; Hayakawa, Takehito ; Tsukada, Kazuaki ; Hashimoto, Kazuyuki ; Sato, Tetsuya ; Asai, Masato ; Toyoshima, Atsushi ; Tanimori, Toru ; Sonoda, Shinya ; Kabuki, Shigeto ; Kimura, Hiroyuki ; Takada, Atsushi ; Mizumoto, Tetsuya ; Takaki, Seiya. / Electron-tracking Compton camera imaging of technetium-95m. In: PloS one. 2018 ; Vol. 13, No. 12.
@article{8929a821c5954b81894b3be7e6e51faa,
title = "Electron-tracking Compton camera imaging of technetium-95m",
abstract = "Imaging was conducted using an electron tracking-Compton camera (ETCC), which measures γ-rays with energies in the range of 200–900 keV from 95m Tc. 95m Tc was produced by the 95 Mo (p, n) 95m Tc reaction on a 95 Mo-enriched target. A method for recycling 95 Mo-enriched molybdenum trioxide was employed, and the recycled yield of 95 Mo was 70{\%}-90{\%}. Images were obtained with the gate of three energies. The results showed that the spatial resolution increases with increasing γ-ray energy, and suggested that the ETCC with high-energy γ-ray emitters such as 95m Tc is useful for the medical imaging of deep tissue and organs in the human body.",
author = "Yuichi Hatsukawa and Takehito Hayakawa and Kazuaki Tsukada and Kazuyuki Hashimoto and Tetsuya Sato and Masato Asai and Atsushi Toyoshima and Toru Tanimori and Shinya Sonoda and Shigeto Kabuki and Hiroyuki Kimura and Atsushi Takada and Tetsuya Mizumoto and Seiya Takaki",
year = "2018",
month = "12",
doi = "10.1371/journal.pone.0208909",
language = "English",
volume = "13",
journal = "PLoS One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "12",

}

TY - JOUR

T1 - Electron-tracking Compton camera imaging of technetium-95m

AU - Hatsukawa, Yuichi

AU - Hayakawa, Takehito

AU - Tsukada, Kazuaki

AU - Hashimoto, Kazuyuki

AU - Sato, Tetsuya

AU - Asai, Masato

AU - Toyoshima, Atsushi

AU - Tanimori, Toru

AU - Sonoda, Shinya

AU - Kabuki, Shigeto

AU - Kimura, Hiroyuki

AU - Takada, Atsushi

AU - Mizumoto, Tetsuya

AU - Takaki, Seiya

PY - 2018/12

Y1 - 2018/12

N2 - Imaging was conducted using an electron tracking-Compton camera (ETCC), which measures γ-rays with energies in the range of 200–900 keV from 95m Tc. 95m Tc was produced by the 95 Mo (p, n) 95m Tc reaction on a 95 Mo-enriched target. A method for recycling 95 Mo-enriched molybdenum trioxide was employed, and the recycled yield of 95 Mo was 70%-90%. Images were obtained with the gate of three energies. The results showed that the spatial resolution increases with increasing γ-ray energy, and suggested that the ETCC with high-energy γ-ray emitters such as 95m Tc is useful for the medical imaging of deep tissue and organs in the human body.

AB - Imaging was conducted using an electron tracking-Compton camera (ETCC), which measures γ-rays with energies in the range of 200–900 keV from 95m Tc. 95m Tc was produced by the 95 Mo (p, n) 95m Tc reaction on a 95 Mo-enriched target. A method for recycling 95 Mo-enriched molybdenum trioxide was employed, and the recycled yield of 95 Mo was 70%-90%. Images were obtained with the gate of three energies. The results showed that the spatial resolution increases with increasing γ-ray energy, and suggested that the ETCC with high-energy γ-ray emitters such as 95m Tc is useful for the medical imaging of deep tissue and organs in the human body.

UR - http://www.scopus.com/inward/record.url?scp=85058237827&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85058237827&partnerID=8YFLogxK

U2 - 10.1371/journal.pone.0208909

DO - 10.1371/journal.pone.0208909

M3 - Article

C2 - 30532248

AN - SCOPUS:85058237827

VL - 13

JO - PLoS One

JF - PLoS One

SN - 1932-6203

IS - 12

M1 - e0208909

ER -