[Electrophysiological diagnosis of multiple sclerosis]

Saeko Inamizu, Shozo Tobimatsu

Research output: Contribution to journalArticlepeer-review


Evoked potentials (EPs) in a daily practice consist of somatosensory evoked potentials (SEP), visual evoked potentials (VEP), auditory brainstem response (ABR) and motor evoked potentials (MEP). EPs can confirm the presence of lesions in patients with suspected involvement, and document the presence of clinically unsuspected lesions in multiple sclerosis (MS) patients. MEP has the highest sensitivity while VEP is the second sensitive. Furthermore, we are able to obtain an increase in sensitivity by using multimodality evoked potentials (MuEP). By doing so, there is a significant correlation between EP abnormalities and Expanded Disability Status Scale. Thus, EPs are useful for the diagnosis or evaluation of MS and predicting neurological disabilities.

Original languageEnglish
Pages (from-to)1983-1988
Number of pages6
JournalNihon rinsho. Japanese journal of clinical medicine
Issue number11
Publication statusPublished - Nov 1 2014

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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