Elimination of pulses and spirals by external forces in Luo-Rudy model

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Abstract

The Luo-Rudy model is one of the standard models for the excitation of cardiac cells. Traveling pulses and spiral waves appear in one-dimensional or two-dimensional Luo-Rudy models. Spiral waves in two-dimensional systems are interpreted as a possible origin of ventricular fibrillation, which is the most serious type of cardiac arrhythmia. Defibrillation is a process to eliminate spiral waves and stop ventricular fibrillation. We perform numerical simulations to eliminate traveling pulses and spiral waves by applying direct current or alternating current to the Luo-Rudy model.

Original languageEnglish
Article number084801
JournalJournal of the Physical Society of Japan
Volume77
Issue number8
DOIs
Publication statusPublished - Aug 2008

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elimination
fibrillation
pulses
arrhythmia
alternating current
direct current
cells
excitation
simulation

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)

Cite this

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abstract = "The Luo-Rudy model is one of the standard models for the excitation of cardiac cells. Traveling pulses and spiral waves appear in one-dimensional or two-dimensional Luo-Rudy models. Spiral waves in two-dimensional systems are interpreted as a possible origin of ventricular fibrillation, which is the most serious type of cardiac arrhythmia. Defibrillation is a process to eliminate spiral waves and stop ventricular fibrillation. We perform numerical simulations to eliminate traveling pulses and spiral waves by applying direct current or alternating current to the Luo-Rudy model.",
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AB - The Luo-Rudy model is one of the standard models for the excitation of cardiac cells. Traveling pulses and spiral waves appear in one-dimensional or two-dimensional Luo-Rudy models. Spiral waves in two-dimensional systems are interpreted as a possible origin of ventricular fibrillation, which is the most serious type of cardiac arrhythmia. Defibrillation is a process to eliminate spiral waves and stop ventricular fibrillation. We perform numerical simulations to eliminate traveling pulses and spiral waves by applying direct current or alternating current to the Luo-Rudy model.

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