This talk presents a mechanism and applications of our developed electrically-induced bubbles. The novelties is that simultaneous local reagent injection and pore formation to the of variety of hardness using bubble cavitation and plasma cavitation. Cavitation and plasma discharge were generated by pulse discharge of microelectrode having special tip structure. Wide dynamic range injection was achieved by the synergistic effect of cavitation of bubble and plasma ablation. The novelty of the technique enables to process not only conductive material but also non-conductive material. Also, the reducing power of hydrogen radical by plasma discharge and the micro-jet caused by collapse of microbubble, and aim at developing a metallization method which does not need a complicated process such as surface treatment. This simultaneous etching and deposition methods provide novel printing method of electrical circuit on wide range of material and contribute to not only bio-medical engineering but also the device fabrications.