Enantio- and regioselective intermolecular benzylic and allylic C-H bond amination

Yota Nishioka, Tatsuya Uchida, Tsutomu Katsuki

Research output: Contribution to journalArticlepeer-review

95 Citations (Scopus)

Abstract

Smooth salen: Ru(CO)-salen complex 1 is an effective catalyst for asymmetric benzylic and allylic C-H bond amination using 2-(trimethylsilyl) ethanesulfonyl azide (SESN3) as the nitrene source. The reaction proceeded with high enantioselectivity and excellent regioselectivity. An ethyl group can be selectively aminated, even in the presence of an n-propyl group. No migration or isomerization of the double bond was observed.

Original languageEnglish
Pages (from-to)1739-1742
Number of pages4
JournalAngewandte Chemie - International Edition
Volume52
Issue number6
DOIs
Publication statusPublished - Feb 4 2013

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

Fingerprint Dive into the research topics of 'Enantio- and regioselective intermolecular benzylic and allylic C-H bond amination'. Together they form a unique fingerprint.

Cite this