Enantioselective [1,2] Wittig rearrangement using an external chiral ligand

Katsuhiko Tomooka, Kyoko Yamamoto, Takeshi Nakai

Research output: Contribution to journalArticlepeer-review

36 Citations (Scopus)

Abstract

Even with only a catalytic amount of chiral bis(dihydrooxazole) 1 as external ligand, the rearrangement of benzyl ethers to alcohols [Eq. (1)] proceeds with high enantioselectivity (over 60 % ee). This reaction represents the first example of an enantioselective [1,2] Wittig rearrangement.

Original languageEnglish
Pages (from-to)3741-3743
Number of pages3
JournalAngewandte Chemie - International Edition
Volume38
Issue number24
DOIs
Publication statusPublished - Dec 16 1999
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

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