A drop in melting point of 21.5°C is induced by the UV-photolytic trans→cis isomerization of the duplex formed between an oligonucleotide bearing two D-threoninol-tethered azobenzene moieties (see picture) in the side chain and its complementary counterpart. On irradiation with visible light, the dissociated single-stranded oligonucleotides regenerate the duplex.
|Number of pages||3|
|Journal||Angewandte Chemie - International Edition|
|Publication status||Published - Jul 16 2001|
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