Enantioselective synthesis of the fully functionalized ABC ring of zoanthenol

Naoki Sugano; Yuuki Koizumi; Go Hirai; Hiroki Oguri; Shoji Kobayashi; Shuji Yamashita; Masahiro Hirama

doi:10.1002/asia.200800079

Enantioselective synthesis of the fully functionalized ABC ring of zoanthenol

Naoki Sugano, Yuuki Koizumi, Go Hirai, Hiroki Oguri, Shoji Kobayashi, Shuji Yamashita, Masahiro Hirama

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Zoanthenol, isolated from Zoanthus sp., possesses an extremely complex architecture including contiguous quaternary carbons. An enantioselective synthesis of the fully functionalized ABC-ring of zoanthenol has been achieved and is described herein. The key features of the synthesis are the enzymatic kinetic optical resolution and the Mizoroki-Heck/Simmons-Smith reaction strategy used to construct the congested asymmetric quaternary carbons.

Original language	English
Pages (from-to)	1549-1557
Number of pages	9
Journal	Chemistry - An Asian Journal
Volume	3
Issue number	8-9
DOIs	https://doi.org/10.1002/asia.200800079
Publication status	Published - Sept 1 2008
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Organic Chemistry

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10.1002/asia.200800079

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abstract = "Zoanthenol, isolated from Zoanthus sp., possesses an extremely complex architecture including contiguous quaternary carbons. An enantioselective synthesis of the fully functionalized ABC-ring of zoanthenol has been achieved and is described herein. The key features of the synthesis are the enzymatic kinetic optical resolution and the Mizoroki-Heck/Simmons-Smith reaction strategy used to construct the congested asymmetric quaternary carbons.",

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AU - Sugano, Naoki

AU - Koizumi, Yuuki

AU - Hirai, Go

AU - Oguri, Hiroki

AU - Kobayashi, Shoji

AU - Yamashita, Shuji

AU - Hirama, Masahiro

PY - 2008/9/1

Y1 - 2008/9/1

N2 - Zoanthenol, isolated from Zoanthus sp., possesses an extremely complex architecture including contiguous quaternary carbons. An enantioselective synthesis of the fully functionalized ABC-ring of zoanthenol has been achieved and is described herein. The key features of the synthesis are the enzymatic kinetic optical resolution and the Mizoroki-Heck/Simmons-Smith reaction strategy used to construct the congested asymmetric quaternary carbons.

AB - Zoanthenol, isolated from Zoanthus sp., possesses an extremely complex architecture including contiguous quaternary carbons. An enantioselective synthesis of the fully functionalized ABC-ring of zoanthenol has been achieved and is described herein. The key features of the synthesis are the enzymatic kinetic optical resolution and the Mizoroki-Heck/Simmons-Smith reaction strategy used to construct the congested asymmetric quaternary carbons.

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Enantioselective synthesis of the fully functionalized ABC ring of zoanthenol

Abstract

All Science Journal Classification (ASJC) codes

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