Endometrial carcinoma in women aged 40 years or younger: A japanese experience

T. Kaku, K. Matsuo, N. Tsukamoto, T. Shimamoto, K. Sugihara, N. Tsuruchi, N. To, T. Kamura, T. Saito, M. Imachi, H. Nakano

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

We report on the clinical and pathologic findings in 17 cases of endometrial carcinoma in Japanese women aged 40 years or younger. Age of the patients ranged from 16 to 40 years, with a median of 35 years. Nine of 17 tumors (52.9%) were stage I or II (FIGO 1988) but 8 (47.1%) were stage III. Four of the 8 patients with stage III disease had pelvic lymph node metastases and one also had para-aortic lymph node metastasis. One patient had metastasis to the ovary and peritoneal cytology was positive in 4 patients. Histologically, 13 of these 17 patients had endometrioid adenocarcinoma, 3 had adenoacanthoma and I had an undifferentiated carcinoma. Ten were well differentiated tumors (G1), 3 were moderately differentiated tumors (G2), and 4 were poorly differentiated tumors (G3). Nine of 17 (52.9%) showed deep myometrial invasion (more than a half of the myometrium) and 5 of 17 (29.4%) demonstrated lymphatic/vascular space invasion. Pelvic and para-aortic lymph node metastases were seen in 4 of 15 (26.7%) and I of 15 (6.7%), respectively. Two of these 17 patients died of disease in a relatively short follow-up period. In our experience there is no difference in the survival rates between patients aged 40 years or younger and those over 40 years.

Original languageEnglish
Pages (from-to)147-153
Number of pages7
JournalInternational Journal of Gynecological Cancer
Volume3
Issue number3
DOIs
Publication statusPublished - May 1993

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Endometrial Neoplasms
Neoplasm Metastasis
Lymph Nodes
Neoplasms
Endometrioid Carcinoma
Myometrium
Blood Vessels
Cell Biology
Ovary
Survival Rate
Carcinoma

All Science Journal Classification (ASJC) codes

  • Oncology
  • Obstetrics and Gynaecology

Cite this

Kaku, T., Matsuo, K., Tsukamoto, N., Shimamoto, T., Sugihara, K., Tsuruchi, N., ... Nakano, H. (1993). Endometrial carcinoma in women aged 40 years or younger: A japanese experience. International Journal of Gynecological Cancer, 3(3), 147-153. https://doi.org/10.1046/j.1525-1438.1993.03030147.x

Endometrial carcinoma in women aged 40 years or younger : A japanese experience. / Kaku, T.; Matsuo, K.; Tsukamoto, N.; Shimamoto, T.; Sugihara, K.; Tsuruchi, N.; To, N.; Kamura, T.; Saito, T.; Imachi, M.; Nakano, H.

In: International Journal of Gynecological Cancer, Vol. 3, No. 3, 05.1993, p. 147-153.

Research output: Contribution to journalArticle

Kaku, T, Matsuo, K, Tsukamoto, N, Shimamoto, T, Sugihara, K, Tsuruchi, N, To, N, Kamura, T, Saito, T, Imachi, M & Nakano, H 1993, 'Endometrial carcinoma in women aged 40 years or younger: A japanese experience', International Journal of Gynecological Cancer, vol. 3, no. 3, pp. 147-153. https://doi.org/10.1046/j.1525-1438.1993.03030147.x
Kaku, T. ; Matsuo, K. ; Tsukamoto, N. ; Shimamoto, T. ; Sugihara, K. ; Tsuruchi, N. ; To, N. ; Kamura, T. ; Saito, T. ; Imachi, M. ; Nakano, H. / Endometrial carcinoma in women aged 40 years or younger : A japanese experience. In: International Journal of Gynecological Cancer. 1993 ; Vol. 3, No. 3. pp. 147-153.
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