Endoscopic ligation of oesophageal varices compared with injection sclerotherapy in primary biliary cirrhosis

K. Tsugawa, Makoto Hashizume, S. Migou, F. Kishihara, H. Kawanaka, M. Tomikawa, K. Tanoue, K. Sugimachi

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background and aims: Oesophageal varices are an important complication in primary biliary cirrhosis (PBC). However, there have yet to be any studies made on treatment of oesophageal varices in PBC. We therefore studied the efficacy and related complications of endoscopic variceal ligation (EVL) and endoscopic injection sclerotherapy (EIS) as an initial treatment in primary biliary cirrhotic patients. Methods: From December 1985 to March 1999, 29 biliary cirrhotic Japanese patients with portal hypertension and oesophageal varices were treated in our clinics. Eleven patients were treated with EVL and EIS, and 18 patients underwent EIS only. The liver function, renal function and respiratory function were studied before and after endoscopic treatment and any complications were also examined. Results: In stages III and IV, significant differences were observed in the serum levels for total bilirubin and γ-glutamic pyruvic transaminase only in the EIS group. Significant differences were observed in the rate of appearance of pyrexia, retrosternal pain and pleural effusion between the EIS and EVL groups. Conclusion: EVL significantly reduced the adverse effects associated with EIS at the initial session in primary biliary cirrhotic patients. (C) 2000 Lippincott Williams and Wilkins.

Original languageEnglish
Pages (from-to)1111-1115
Number of pages5
JournalEuropean Journal of Gastroenterology and Hepatology
Volume12
Issue number10
DOIs
Publication statusPublished - Jan 1 2000

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Sclerotherapy
Esophageal and Gastric Varices
Biliary Liver Cirrhosis
Ligation
Injections
Portal Hypertension
Pleural Effusion
Alanine Transaminase
Bilirubin
Fever
Therapeutics
Kidney
Pain
Liver
Serum

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

Cite this

Endoscopic ligation of oesophageal varices compared with injection sclerotherapy in primary biliary cirrhosis. / Tsugawa, K.; Hashizume, Makoto; Migou, S.; Kishihara, F.; Kawanaka, H.; Tomikawa, M.; Tanoue, K.; Sugimachi, K.

In: European Journal of Gastroenterology and Hepatology, Vol. 12, No. 10, 01.01.2000, p. 1111-1115.

Research output: Contribution to journalArticle

Tsugawa, K, Hashizume, M, Migou, S, Kishihara, F, Kawanaka, H, Tomikawa, M, Tanoue, K & Sugimachi, K 2000, 'Endoscopic ligation of oesophageal varices compared with injection sclerotherapy in primary biliary cirrhosis', European Journal of Gastroenterology and Hepatology, vol. 12, no. 10, pp. 1111-1115. https://doi.org/10.1097/00042737-200012100-00007
Tsugawa, K. ; Hashizume, Makoto ; Migou, S. ; Kishihara, F. ; Kawanaka, H. ; Tomikawa, M. ; Tanoue, K. ; Sugimachi, K. / Endoscopic ligation of oesophageal varices compared with injection sclerotherapy in primary biliary cirrhosis. In: European Journal of Gastroenterology and Hepatology. 2000 ; Vol. 12, No. 10. pp. 1111-1115.
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