Endoscopic submucosal dissection with a grasping-type scissors for early colorectal epithelial neoplasms: a large single-center experience

Kazuya Akahoshi, Yuki Shiratsuchi, Masafumi Oya, Hidenobu Koga, Masaru Kubokawa, Naotaka Nakama, Kazuaki Akahoshi, Eikichi Ihara

Research output: Contribution to journalArticle

Abstract

Background and aims: The Clutch Cutter (CC) can grasp, pull, coagulate, and incise targeted tissue with the use of electrosurgical current. It was developed as a biopsy technique to reduce the technical difficulty of endoscopic submucosal dissection (ESD) with knives. The aim of this study was to evaluate the efficacy and safety of ESD using the CC (ESD-CC) for early colorectal epithelial neoplasms (ECENs). Methods: In this prospective study, we enrolled 437 consecutive patients with a diagnosis of ECEN between January 2009 and January 2018. They all satisfied the Japanese colorectal cancer treatment guidelines for ESD; namely, confirmation by preliminary endoscopy, EUS, and endoscopic biopsy. The CC was used for all steps of ESD (mucosal incision, submucosal dissection, and hemostatic treatment); therapeutic efficacy and safety were assessed. Results: The en bloc resection rate was 99.3% (434/437), and the R0 resection rate was 87.0% (380/437). The mean operating time was 88.3 minutes. Perforation occurred in 10 cases (2.3%) and was managed with conservative medical treatment. Post-ESD-CC bleeding occurred in 10 cases (2.3%) and was successfully treated by endoscopic hemostatic treatment. Conclusions: ESD-CC is a technically efficient, safe, and easy method for resecting ECEN.

Original languageEnglish
Pages (from-to)486-492
Number of pages7
JournalVideoGIE
Volume4
Issue number10
DOIs
Publication statusPublished - Oct 1 2019

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Glandular and Epithelial Neoplasms
Colorectal Neoplasms
Hemostatics
Biopsy
Safety
Therapeutics
Endoscopy
Endoscopic Mucosal Resection
Dissection
Prospective Studies
Guidelines
Hemorrhage

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology

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Endoscopic submucosal dissection with a grasping-type scissors for early colorectal epithelial neoplasms : a large single-center experience. / Akahoshi, Kazuya; Shiratsuchi, Yuki; Oya, Masafumi; Koga, Hidenobu; Kubokawa, Masaru; Nakama, Naotaka; Akahoshi, Kazuaki; Ihara, Eikichi.

In: VideoGIE, Vol. 4, No. 10, 01.10.2019, p. 486-492.

Research output: Contribution to journalArticle

Akahoshi, Kazuya ; Shiratsuchi, Yuki ; Oya, Masafumi ; Koga, Hidenobu ; Kubokawa, Masaru ; Nakama, Naotaka ; Akahoshi, Kazuaki ; Ihara, Eikichi. / Endoscopic submucosal dissection with a grasping-type scissors for early colorectal epithelial neoplasms : a large single-center experience. In: VideoGIE. 2019 ; Vol. 4, No. 10. pp. 486-492.
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