TY - JOUR
T1 - Endoscopic submucosal dissection with a grasping-type scissors for early colorectal epithelial neoplasms
T2 - a large single-center experience
AU - Akahoshi, Kazuya
AU - Shiratsuchi, Yuki
AU - Oya, Masafumi
AU - Koga, Hidenobu
AU - Kubokawa, Masaru
AU - Nakama, Naotaka
AU - Akahoshi, Kazuaki
AU - Ihara, Eikichi
N1 - Funding Information:
We thank Cathel Ker, BSc, PhD, from Edanz Group ( www.edanzediting.com/ac ) for editing a draft of this manuscript. This research was conducted with the assistance of a research grant from Aso Iizuka Hospital.
Publisher Copyright:
© 2019 American Society for Gastrointestinal Endoscopy
PY - 2019/10
Y1 - 2019/10
N2 - Background and aims: The Clutch Cutter (CC) can grasp, pull, coagulate, and incise targeted tissue with the use of electrosurgical current. It was developed as a biopsy technique to reduce the technical difficulty of endoscopic submucosal dissection (ESD) with knives. The aim of this study was to evaluate the efficacy and safety of ESD using the CC (ESD-CC) for early colorectal epithelial neoplasms (ECENs). Methods: In this prospective study, we enrolled 437 consecutive patients with a diagnosis of ECEN between January 2009 and January 2018. They all satisfied the Japanese colorectal cancer treatment guidelines for ESD; namely, confirmation by preliminary endoscopy, EUS, and endoscopic biopsy. The CC was used for all steps of ESD (mucosal incision, submucosal dissection, and hemostatic treatment); therapeutic efficacy and safety were assessed. Results: The en bloc resection rate was 99.3% (434/437), and the R0 resection rate was 87.0% (380/437). The mean operating time was 88.3 minutes. Perforation occurred in 10 cases (2.3%) and was managed with conservative medical treatment. Post-ESD-CC bleeding occurred in 10 cases (2.3%) and was successfully treated by endoscopic hemostatic treatment. Conclusions: ESD-CC is a technically efficient, safe, and easy method for resecting ECEN.
AB - Background and aims: The Clutch Cutter (CC) can grasp, pull, coagulate, and incise targeted tissue with the use of electrosurgical current. It was developed as a biopsy technique to reduce the technical difficulty of endoscopic submucosal dissection (ESD) with knives. The aim of this study was to evaluate the efficacy and safety of ESD using the CC (ESD-CC) for early colorectal epithelial neoplasms (ECENs). Methods: In this prospective study, we enrolled 437 consecutive patients with a diagnosis of ECEN between January 2009 and January 2018. They all satisfied the Japanese colorectal cancer treatment guidelines for ESD; namely, confirmation by preliminary endoscopy, EUS, and endoscopic biopsy. The CC was used for all steps of ESD (mucosal incision, submucosal dissection, and hemostatic treatment); therapeutic efficacy and safety were assessed. Results: The en bloc resection rate was 99.3% (434/437), and the R0 resection rate was 87.0% (380/437). The mean operating time was 88.3 minutes. Perforation occurred in 10 cases (2.3%) and was managed with conservative medical treatment. Post-ESD-CC bleeding occurred in 10 cases (2.3%) and was successfully treated by endoscopic hemostatic treatment. Conclusions: ESD-CC is a technically efficient, safe, and easy method for resecting ECEN.
UR - http://www.scopus.com/inward/record.url?scp=85068261069&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85068261069&partnerID=8YFLogxK
U2 - 10.1016/j.vgie.2019.05.003
DO - 10.1016/j.vgie.2019.05.003
M3 - Article
AN - SCOPUS:85068261069
SN - 2468-4481
VL - 4
SP - 486
EP - 492
JO - VideoGIE
JF - VideoGIE
IS - 10
ER -
