Endoscopic ultrasound-guided fine-needle aspiration for the diagnosis of peripancreatic tuberculous lymphadenitis

Soichi Itaba, Shigetaka Yoshinaga, Kazuhiko Nakamura, Takahiro Mizutani, Kuniomi Honda, Ryoichi Takayanagi, Kinya Yamada

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The percentage of patients with atypical extrapulmonary forms of tuberculosis has been increasing. Among extrapulmonary tuberculosis cases, tuberculosis of the pancreas and peripancreatic lymph nodes is a rare clinical entity. Here, we present a case of peripancreatic tuberculous lymphadenitis diagnosed by endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) both cytologically and microbiologically. A 23-year-old man had a 1-week history of epigastralgia and low-grade fever. Subsequently, he was found to have an abnormality on abdominal ultrasound. A computed tomography scan of the abdomen showed a solitary mass consisting of multiple cystic components with rim enhancement in the peripancreatic portion contiguous to the gall bladder. Endoscopic ultrasound-guided fine-needle aspiration was performed to confirm the diagnosis. The cytological examination revealed epithelioid cells with caseous necrosis, indicating tuberculosis. The aspirated fluid was positive by polymerase chain reaction (PCR) analysis and culture for Mycobacterium tuberculosis. Antituberculosis therapy with isoniazid, rifampicin, ethambutol, and pyrazinamide was started based on the PCR and cytology results, and a good response to the treatment was noted. Endoscopic ultrasound-guided fine-needle aspiration cytology with PCR analysis is very useful for the diagnosis of peripancreatic tuberculosis.

Original languageEnglish
Pages (from-to)83-86
Number of pages4
JournalJournal of gastroenterology
Volume42
Issue number1
DOIs
Publication statusPublished - Jan 1 2007

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Endoscopic Ultrasound-Guided Fine Needle Aspiration
Lymph Node Tuberculosis
Tuberculosis
Polymerase Chain Reaction
Cell Biology
Pyrazinamide
Epithelioid Cells
Ethambutol
Isoniazid
Rifampin
Mycobacterium tuberculosis
Abdomen
Pancreas
Urinary Bladder
Fever
Necrosis
Lymph Nodes
Tomography
Therapeutics

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

Endoscopic ultrasound-guided fine-needle aspiration for the diagnosis of peripancreatic tuberculous lymphadenitis. / Itaba, Soichi; Yoshinaga, Shigetaka; Nakamura, Kazuhiko; Mizutani, Takahiro; Honda, Kuniomi; Takayanagi, Ryoichi; Yamada, Kinya.

In: Journal of gastroenterology, Vol. 42, No. 1, 01.01.2007, p. 83-86.

Research output: Contribution to journalArticle

Itaba, S, Yoshinaga, S, Nakamura, K, Mizutani, T, Honda, K, Takayanagi, R & Yamada, K 2007, 'Endoscopic ultrasound-guided fine-needle aspiration for the diagnosis of peripancreatic tuberculous lymphadenitis', Journal of gastroenterology, vol. 42, no. 1, pp. 83-86. https://doi.org/10.1007/s00535-006-1913-z
Itaba, Soichi ; Yoshinaga, Shigetaka ; Nakamura, Kazuhiko ; Mizutani, Takahiro ; Honda, Kuniomi ; Takayanagi, Ryoichi ; Yamada, Kinya. / Endoscopic ultrasound-guided fine-needle aspiration for the diagnosis of peripancreatic tuberculous lymphadenitis. In: Journal of gastroenterology. 2007 ; Vol. 42, No. 1. pp. 83-86.
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