Enhancement of cell function through heterotypic cell-cell interactions using E-cadherin-expressing NIH3T3 cells

Akira Ito; Takehiko Kiyohara; Yoshinori Kawabe; Hiroyuki Ijima; Masamichi Kamihira

doi:10.1263/jbb.105.679

Enhancement of cell function through heterotypic cell-cell interactions using E-cadherin-expressing NIH3T3 cells

Akira Ito, Takehiko Kiyohara, Yoshinori Kawabe, Hiroyuki Ijima, Masamichi Kamihira

Molecular and Biochemical Systems Engineering

Research output: Contribution to journal › Article

11 Citations (Scopus)

Abstract

An epithelial cell adhesion molecule, E-cadherin was expressed in NIH3T3 fibroblasts, and cell-cell interactions between keratinocytes and fibroblasts, or between hepatocytes and fibroblasts were artificially engineered. When the E-cadherin-expressing NIH3T3 cells were co-cultured with rat hepatocytes, the cell-cell contacts were formed with high frequency, and enhanced albumin secretion was observed.

Original language	English
Pages (from-to)	679-682
Number of pages	4
Journal	Journal of Bioscience and Bioengineering
Volume	105
Issue number	6
DOIs	https://doi.org/10.1263/jbb.105.679
Publication status	Published - Jun 1 2008

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All Science Journal Classification (ASJC) codes

Biotechnology
Bioengineering
Applied Microbiology and Biotechnology

Cite this

Ito, A., Kiyohara, T., Kawabe, Y., Ijima, H., & Kamihira, M. (2008). Enhancement of cell function through heterotypic cell-cell interactions using E-cadherin-expressing NIH3T3 cells. Journal of Bioscience and Bioengineering, 105(6), 679-682. https://doi.org/10.1263/jbb.105.679

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10.1263/jbb.105.679