Enhancement of disease resistance to Magnaporthe grisea in rice by accumulation of hydroxy linoleic acid

Asanori Yara, Takashi Yaeno, Jean Luc Montillet, Morifumi Hasegawa, Shigemi Seo, Kensuke Kusumi, Koh Iba

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Linoleic acid (18:2) and linolenic acid (18:3) are sources for various oxidized metabolites called oxylipins, some of which inhibit growth of fungal pathogens. In a previous study, we found disease resistance to rice blast fungus Magnaporthe grisea enhanced in 18:2-accumulating transgenic rice (F78Ri) in which the conversion from 18:2 to 18:3 was suppressed. Here, we demonstrate that 18:2-derived hydroperoxides and hydroxides (HPODEs and HODEs, respectively) inhibit growth of M. grisea more strongly than their 18:3-derived counterparts. Furthermore, in F78Ri plants, the endogenous levels of HPODEs and HODEs increased significantly, compared with wild-type plants. These results suggest that the increased accumulation of antifungal oxylipins, such as HPODEs and HODEs, causes the enhancement of disease resistance against M. grisea.

Original languageEnglish
Pages (from-to)344-347
Number of pages4
JournalBiochemical and Biophysical Research Communications
Volume370
Issue number2
DOIs
Publication statusPublished - May 30 2008

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Oxylipins
Magnaporthe
Disease Resistance
Linoleic Acid
Hydroxides
alpha-Linolenic Acid
Pathogens
Metabolites
Fungi
Hydrogen Peroxide
Growth
Oryza

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

Cite this

Enhancement of disease resistance to Magnaporthe grisea in rice by accumulation of hydroxy linoleic acid. / Yara, Asanori; Yaeno, Takashi; Montillet, Jean Luc; Hasegawa, Morifumi; Seo, Shigemi; Kusumi, Kensuke; Iba, Koh.

In: Biochemical and Biophysical Research Communications, Vol. 370, No. 2, 30.05.2008, p. 344-347.

Research output: Contribution to journalArticle

Yara, Asanori ; Yaeno, Takashi ; Montillet, Jean Luc ; Hasegawa, Morifumi ; Seo, Shigemi ; Kusumi, Kensuke ; Iba, Koh. / Enhancement of disease resistance to Magnaporthe grisea in rice by accumulation of hydroxy linoleic acid. In: Biochemical and Biophysical Research Communications. 2008 ; Vol. 370, No. 2. pp. 344-347.
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