TY - GEN
T1 - Enhancement of sensitivity of coulometric detection usng a one-electrode system
AU - Ikemoto, K.
AU - Kojima, K.
AU - Sassa, F.
AU - Yokokawa, M.
AU - Suzuki, H.
N1 - Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2011
Y1 - 2011
N2 - Coulometric analysis is effective in the analysis of an analyte in a liquid plug of a very small volume. However, in the conventional coulometric detection, it took time to collect analyte molecules dissolved in the solution. To solve this problem, we used a novel method to achieve significant enhancement of sensitivity by using a one-electrode system. As a model analyte, hydrogen peroxide was oxidized in a flow channel and silver was deposited simultaneously on another electrode in another flow channel. Coulometric detection of the deposited silver showed a step change of generated charge. As a result, measurement time was reduced significantly (less than 2 s), although conventional methods took more than 60 s to achieve the same sensitivity. This shorter measurement time also suppressed the influence of background noise, resulting in significant lowering of the detection limit.
AB - Coulometric analysis is effective in the analysis of an analyte in a liquid plug of a very small volume. However, in the conventional coulometric detection, it took time to collect analyte molecules dissolved in the solution. To solve this problem, we used a novel method to achieve significant enhancement of sensitivity by using a one-electrode system. As a model analyte, hydrogen peroxide was oxidized in a flow channel and silver was deposited simultaneously on another electrode in another flow channel. Coulometric detection of the deposited silver showed a step change of generated charge. As a result, measurement time was reduced significantly (less than 2 s), although conventional methods took more than 60 s to achieve the same sensitivity. This shorter measurement time also suppressed the influence of background noise, resulting in significant lowering of the detection limit.
UR - http://www.scopus.com/inward/record.url?scp=80052119283&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80052119283&partnerID=8YFLogxK
U2 - 10.1109/TRANSDUCERS.2011.5969242
DO - 10.1109/TRANSDUCERS.2011.5969242
M3 - Conference contribution
AN - SCOPUS:80052119283
SN - 9781457701573
T3 - 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
SP - 1962
EP - 1965
BT - 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
T2 - 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
Y2 - 5 June 2011 through 9 June 2011
ER -