Epidemiologic application of pulsed-field gel electrophoresis to an outbreak of Campylobacter fetus meningitis in a neonatal intensive care unit

Tatsuya Morooka, Akiko Umeda, Masaki Fujita, Hiromi Matano, Shuji Fujimoto, Ko Yukitake, Kazunobu Amako, Teiichi Oda

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

An outbreak of nosocomial Campylobacter fetus meningitis occurred in a neonatal intensive care unit (NICU). Eight C. fetus strains were isolated from 4 infants with meningitis, the mother of the index patient and 2 infants who were asymptomatic intestinal carriers. The pulsed-field gel electrophoresis (PFGE) patterns with the restriction endonucleases SmaI and SalI were found to be identical for the nosocomial C. fetus isolates, but the patterns were different from those of sporadic strains. These nosocomial strains were strongly suspected to be a single strain. The finding revealed that the index patient was infected by the mother, and that the outbreak developed from this patient by cross-infection. This is the first confirmed nosocomial C. fetus meningitis outbreak spread by cross-infection in a NICU.

Original languageEnglish
Pages (from-to)269-270
Number of pages2
JournalScandinavian Journal of Infectious Diseases
Volume28
Issue number3
DOIs
Publication statusPublished - Jan 1 1996

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Campylobacter fetus
Pulsed Field Gel Electrophoresis
Neonatal Intensive Care Units
Meningitis
Disease Outbreaks
Cross Infection
Mothers
DNA Restriction Enzymes

All Science Journal Classification (ASJC) codes

  • Immunology and Microbiology(all)
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Epidemiologic application of pulsed-field gel electrophoresis to an outbreak of Campylobacter fetus meningitis in a neonatal intensive care unit. / Morooka, Tatsuya; Umeda, Akiko; Fujita, Masaki; Matano, Hiromi; Fujimoto, Shuji; Yukitake, Ko; Amako, Kazunobu; Oda, Teiichi.

In: Scandinavian Journal of Infectious Diseases, Vol. 28, No. 3, 01.01.1996, p. 269-270.

Research output: Contribution to journalArticle

Morooka, Tatsuya ; Umeda, Akiko ; Fujita, Masaki ; Matano, Hiromi ; Fujimoto, Shuji ; Yukitake, Ko ; Amako, Kazunobu ; Oda, Teiichi. / Epidemiologic application of pulsed-field gel electrophoresis to an outbreak of Campylobacter fetus meningitis in a neonatal intensive care unit. In: Scandinavian Journal of Infectious Diseases. 1996 ; Vol. 28, No. 3. pp. 269-270.
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