Epidemiological trends of imported infectious diseases in Japan: Analysis of imported 2-year infectious disease registry data

Satoshi Kutsuna, Yusuke Asai, Kei Yamamoto, Michinori Shirano, Keiji Konishi, Tomohiro Asaoka, Masaya Yamato, Yukiko Katsuragi, Yudai Yamamoto, Toshinori Sahara, Aya Tamiya, Fukumi Nakamura-Uchiyama, Naoya Sakamoto, Atsushi Kosaka, Takuya Washino, Ryota Hase, Haruki Mito, Takashi Kurita, Koh Shinohara, Tsunehiro ShimizuFumihiro Kodama, Atsushi Nagasaka, Taku Ogawa, Kei Kasahara, Yukihiro Yoshimura, Natsuo Tachikawa, Kyoko Yokota, N. S. Yuka Murai, Ippei Sakamaki, Chihiro Hasegawa, Yusuke Yoshimi, Kazuhiro Toyoda, Tatsuro Mitsuhashi, Norio Ohmagari

Research output: Contribution to journalArticlepeer-review


Introduction: The epidemiology of infectious diseases in Japan remains undefined despite the increasing tourism. GeoSentinel, an epidemiological surveillance system for reporting imported infectious diseases, has only two participating facilities in Japan. Although the number of infectious diseases is reported by the National Institute of Infectious Diseases, there is no detailed clinical information about these cases. Therefore, we established J-RIDA (Japan Registry for Infectious Diseases from Abroad) to clarify the status of imported infectious diseases in Japan and provide detailed information. Methods: J-RIDA was started as a registry of imported infectious diseases. Case registration began in October 2017. Between October 2017 and September 2019, 15 medical institutions participated in this clinical study. The registry collected information about the patient's age, sex, nationality, chief complaint, consultation date, date of onset, whether visit was made to a travel clinic before travel, blood test results (if samples were collected), travel history, and final diagnosis. Results: Of the 3046 cases included in this study, 46.7% to Southeast Asia, 13.0% to Africa, 13.7% to East Asia, 11.5% to South Asia, 7.5% to Europe, 3.8% to Central and South America, 4.6% to North America, 3.9% to Oceania, and 2.8% to Central and west Asia. More than 85% of chief complaints were fever and general symptoms, gastrointestinal symptoms, respiratory symptoms, or dermatologic problems. The most common diseases were travelers’ diarrhea, animal bite, upper respiratory infection, influenza, and dengue fever. Conclusions: We summarized two-year cases registered in Japan's imported infectious disease registry. These results will significantly contribute to the epidemiology in Japan.

Original languageEnglish
Pages (from-to)632-638
Number of pages7
JournalJournal of Infection and Chemotherapy
Issue number4
Publication statusPublished - Apr 2021

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Pharmacology (medical)
  • Infectious Diseases

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