Epigenetic Regulation of Human Neural Stem Cell Differentiation

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Emerging evidence has demonstrated that epigenetic programs influence many aspects of neural stem cell (NSC) behavior, including proliferation and differentiation. It is becoming apparent that epigenetic mechanisms, such as DNA methylation, histone modifications, and noncoding RNA expression, are spatiotemporally regulated and that these intracellular programs, in concert with extracellular signals, ensure appropriate gene activation. Here we summarize recent advances in understanding of the epigenetic regulation of human NSCs directly isolated from the brain or produced from pluripotent stem cells (embryonic and induced pluripotent stem cells, respectively).

Original languageEnglish
Title of host publicationResults and Problems in Cell Differentiation
PublisherSpringer Verlag
Pages125-136
Number of pages12
DOIs
Publication statusPublished - 2018

Publication series

NameResults and Problems in Cell Differentiation
Volume66
ISSN (Print)0080-1844
ISSN (Electronic)1861-0412

All Science Journal Classification (ASJC) codes

  • Developmental Biology
  • Cell Biology

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  • Cite this

    Honda, M., Nakashima, K., & Katada, S. (2018). Epigenetic Regulation of Human Neural Stem Cell Differentiation. In Results and Problems in Cell Differentiation (pp. 125-136). (Results and Problems in Cell Differentiation; Vol. 66). Springer Verlag. https://doi.org/10.1007/978-3-319-93485-3_5