Epstein-barr virus load in cerebrospinal fluid of patients with chronic active epstein-barr virus infection

Shouichi Ohga, Masafumi Sanefuji, Masataka Ishimura, Akihiko Nomura, Hiroyuki Torisu, Ryutaro Kira, Hidetoshi Takada, Yumi Mizuno, Yukumasa Kazuyama, Toshiro Hara

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Chronic active Epstein-Barr virus (EBV) infection is a rare chronic mononucleosis syndrome involving clonally proliferating EBV-infected T-/NK-cells. EBV DNA was quantified in nonpleocytotic cerebrospinal fluid (CSF) of 9 patients. Three patients with neurologic and/or neuroimaging abnormalities showed high CSF copy numbers. In 1 patient, CSF copy number exceeded the peripheral blood value. CSF EBV-load may predict the central nervous system involvement of EBVT-/NK-cells.

Original languageEnglish
Pages (from-to)1027-1030
Number of pages4
JournalPediatric Infectious Disease Journal
Volume27
Issue number11
DOIs
Publication statusPublished - Nov 2008

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Epstein-barr virus load in cerebrospinal fluid of patients with chronic active epstein-barr virus infection'. Together they form a unique fingerprint.

Cite this