Eradication of large gastric varices by sclerotherapy combined with percutaneous transhepatic obliteration

Makoto Hashizume, Kouji Tsugawa, Shinichiro Migo, Morimasa Tomikawa, Fumiaki Kishihara, Hirofumi Kawanaka, Kazuo Tanoue, Masayuki Ohta, Keizo Sugimachi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background/Aims: The long-term results of a combination therapy of sclerotherapy with percutaneus transhepatic obliteration (PTO) was reviewed in 37 patients with large gastric varices. The study suggests that sclerotherapy combined with PTO can safely and effectively eradicate large gastric varices as an alternative approach to surgery. Complete eradication has also been shown to prevent the recurrence of gastric varices. Material and Methods: The long-term results of a combination therapy of sclerotherapy with PTO was reviewed in 37 patients with large gastric varices. Results: Complete eradication of the gastric varices was obtained in 26 patients (70.3%). There was no recurrence of the varices in whom complete eradication had been obtained, but in 11 patients with incomplete eradication gastric varices recurred during the mean follow-up period of 37.5 months. Bleeding occurred in 4 after the treatment and one patient died of massive bleeding from the recurrent gastric varices. There were no major complications with the procedure except for one who had a peripheral pulmonary arterial embolization as a result of a coil used for the PTO. Conclusion: This study suggests that sclerotherapy combined with PTO can effectively and safely eradicate large gastric varices and is an alternative approach to surgery for treating patients with gastric varices. It is also shown that complete eradication leads to a prevention of recurrence of gastric varices.

Original languageEnglish
Pages (from-to)221-226
Number of pages6
JournalHepato-gastroenterology
Volume44
Issue number13
Publication statusPublished - Mar 11 1997

Fingerprint

Sclerotherapy
Esophageal and Gastric Varices
Recurrence
Hemorrhage
Varicose Veins
Therapeutics
Lung

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

Cite this

Hashizume, M., Tsugawa, K., Migo, S., Tomikawa, M., Kishihara, F., Kawanaka, H., ... Sugimachi, K. (1997). Eradication of large gastric varices by sclerotherapy combined with percutaneous transhepatic obliteration. Hepato-gastroenterology, 44(13), 221-226.

Eradication of large gastric varices by sclerotherapy combined with percutaneous transhepatic obliteration. / Hashizume, Makoto; Tsugawa, Kouji; Migo, Shinichiro; Tomikawa, Morimasa; Kishihara, Fumiaki; Kawanaka, Hirofumi; Tanoue, Kazuo; Ohta, Masayuki; Sugimachi, Keizo.

In: Hepato-gastroenterology, Vol. 44, No. 13, 11.03.1997, p. 221-226.

Research output: Contribution to journalArticle

Hashizume, M, Tsugawa, K, Migo, S, Tomikawa, M, Kishihara, F, Kawanaka, H, Tanoue, K, Ohta, M & Sugimachi, K 1997, 'Eradication of large gastric varices by sclerotherapy combined with percutaneous transhepatic obliteration', Hepato-gastroenterology, vol. 44, no. 13, pp. 221-226.
Hashizume M, Tsugawa K, Migo S, Tomikawa M, Kishihara F, Kawanaka H et al. Eradication of large gastric varices by sclerotherapy combined with percutaneous transhepatic obliteration. Hepato-gastroenterology. 1997 Mar 11;44(13):221-226.
Hashizume, Makoto ; Tsugawa, Kouji ; Migo, Shinichiro ; Tomikawa, Morimasa ; Kishihara, Fumiaki ; Kawanaka, Hirofumi ; Tanoue, Kazuo ; Ohta, Masayuki ; Sugimachi, Keizo. / Eradication of large gastric varices by sclerotherapy combined with percutaneous transhepatic obliteration. In: Hepato-gastroenterology. 1997 ; Vol. 44, No. 13. pp. 221-226.
@article{8cc4f69f91894a3b81ff966d66d4a27d,
title = "Eradication of large gastric varices by sclerotherapy combined with percutaneous transhepatic obliteration",
abstract = "Background/Aims: The long-term results of a combination therapy of sclerotherapy with percutaneus transhepatic obliteration (PTO) was reviewed in 37 patients with large gastric varices. The study suggests that sclerotherapy combined with PTO can safely and effectively eradicate large gastric varices as an alternative approach to surgery. Complete eradication has also been shown to prevent the recurrence of gastric varices. Material and Methods: The long-term results of a combination therapy of sclerotherapy with PTO was reviewed in 37 patients with large gastric varices. Results: Complete eradication of the gastric varices was obtained in 26 patients (70.3{\%}). There was no recurrence of the varices in whom complete eradication had been obtained, but in 11 patients with incomplete eradication gastric varices recurred during the mean follow-up period of 37.5 months. Bleeding occurred in 4 after the treatment and one patient died of massive bleeding from the recurrent gastric varices. There were no major complications with the procedure except for one who had a peripheral pulmonary arterial embolization as a result of a coil used for the PTO. Conclusion: This study suggests that sclerotherapy combined with PTO can effectively and safely eradicate large gastric varices and is an alternative approach to surgery for treating patients with gastric varices. It is also shown that complete eradication leads to a prevention of recurrence of gastric varices.",
author = "Makoto Hashizume and Kouji Tsugawa and Shinichiro Migo and Morimasa Tomikawa and Fumiaki Kishihara and Hirofumi Kawanaka and Kazuo Tanoue and Masayuki Ohta and Keizo Sugimachi",
year = "1997",
month = "3",
day = "11",
language = "English",
volume = "44",
pages = "221--226",
journal = "Acta hepato-splenologica",
issn = "0172-6390",
publisher = "H.G.E. Update Medical Publishing Ltd.",
number = "13",

}

TY - JOUR

T1 - Eradication of large gastric varices by sclerotherapy combined with percutaneous transhepatic obliteration

AU - Hashizume, Makoto

AU - Tsugawa, Kouji

AU - Migo, Shinichiro

AU - Tomikawa, Morimasa

AU - Kishihara, Fumiaki

AU - Kawanaka, Hirofumi

AU - Tanoue, Kazuo

AU - Ohta, Masayuki

AU - Sugimachi, Keizo

PY - 1997/3/11

Y1 - 1997/3/11

N2 - Background/Aims: The long-term results of a combination therapy of sclerotherapy with percutaneus transhepatic obliteration (PTO) was reviewed in 37 patients with large gastric varices. The study suggests that sclerotherapy combined with PTO can safely and effectively eradicate large gastric varices as an alternative approach to surgery. Complete eradication has also been shown to prevent the recurrence of gastric varices. Material and Methods: The long-term results of a combination therapy of sclerotherapy with PTO was reviewed in 37 patients with large gastric varices. Results: Complete eradication of the gastric varices was obtained in 26 patients (70.3%). There was no recurrence of the varices in whom complete eradication had been obtained, but in 11 patients with incomplete eradication gastric varices recurred during the mean follow-up period of 37.5 months. Bleeding occurred in 4 after the treatment and one patient died of massive bleeding from the recurrent gastric varices. There were no major complications with the procedure except for one who had a peripheral pulmonary arterial embolization as a result of a coil used for the PTO. Conclusion: This study suggests that sclerotherapy combined with PTO can effectively and safely eradicate large gastric varices and is an alternative approach to surgery for treating patients with gastric varices. It is also shown that complete eradication leads to a prevention of recurrence of gastric varices.

AB - Background/Aims: The long-term results of a combination therapy of sclerotherapy with percutaneus transhepatic obliteration (PTO) was reviewed in 37 patients with large gastric varices. The study suggests that sclerotherapy combined with PTO can safely and effectively eradicate large gastric varices as an alternative approach to surgery. Complete eradication has also been shown to prevent the recurrence of gastric varices. Material and Methods: The long-term results of a combination therapy of sclerotherapy with PTO was reviewed in 37 patients with large gastric varices. Results: Complete eradication of the gastric varices was obtained in 26 patients (70.3%). There was no recurrence of the varices in whom complete eradication had been obtained, but in 11 patients with incomplete eradication gastric varices recurred during the mean follow-up period of 37.5 months. Bleeding occurred in 4 after the treatment and one patient died of massive bleeding from the recurrent gastric varices. There were no major complications with the procedure except for one who had a peripheral pulmonary arterial embolization as a result of a coil used for the PTO. Conclusion: This study suggests that sclerotherapy combined with PTO can effectively and safely eradicate large gastric varices and is an alternative approach to surgery for treating patients with gastric varices. It is also shown that complete eradication leads to a prevention of recurrence of gastric varices.

UR - http://www.scopus.com/inward/record.url?scp=0031045458&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031045458&partnerID=8YFLogxK

M3 - Article

C2 - 9058148

AN - SCOPUS:0031045458

VL - 44

SP - 221

EP - 226

JO - Acta hepato-splenologica

JF - Acta hepato-splenologica

SN - 0172-6390

IS - 13

ER -