Establishing the cut-off scores for the severity ranges of schizophrenia on the BPRS-6 scale: findings from the REAP-AP

Seon Cheol Park; Eun Young Jang; Kiwon Kim; Hoseon Lee; Joonho Choi; Amitava Dan; Arshad Hussain; Andi Jayalangkara Tanra; Takahiro A. Kato; Kok Yoon Chee; Sih Ku Lin; Chay Hoon Tan; Afzal Javed; Norman Sartorius; Naotaka Shinfuku; Yong Chon Park

doi:10.1080/24750573.2019.1695994

Establishing the cut-off scores for the severity ranges of schizophrenia on the BPRS-6 scale: findings from the REAP-AP

Seon Cheol Park, Eun Young Jang, Kiwon Kim, Hoseon Lee, Joonho Choi, Amitava Dan, Arshad Hussain, Andi Jayalangkara Tanra, Takahiro A. Kato, Kok Yoon Chee, Sih Ku Lin, Chay Hoon Tan, Afzal Javed, Norman Sartorius, Naotaka Shinfuku, Yong Chon Park

Neuro-Psychiatry

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: Using data from the Research on Asian Psychotropic Prescription Patterns for Antipsychotics (REAP-AP), our study aimed to establish the remission and severity ranges (mild, moderate, and severe) of schizophrenia on the Brief Psychiatric Rating Scale-6 (BPRS-6). Methods: A total of 1,438 patients with schizophrenia from India, Indonesia, Japan, Malaysia, and Taiwan were enrolled in the study. Using the receiver operating characteristic (ROC) curve analyses, the optimal cut-off scores for the remission and severity ranges on the BPRS-6 were established. Results: The scalability of the BPRS-6 was considered to have an acceptable “unidimensionality” (coefficient of scalability = 0.43). The cut-off scores for the remission of schizophrenia and mild, moderate, and severe schizophrenia can be optimally defined as the BPRS-6 total score of <5, 5–9, 10–19 and >20, respectively. Conclusion: The BPRS-6 can be a promising, brief, and unidimensional rating scale to supplement the measurement-based care of schizophrenia.

Original language	English
Pages (from-to)	895-898
Number of pages	4
Journal	Psychiatry and Clinical Psychopharmacology
Volume	29
Issue number	4
DOIs	https://doi.org/10.1080/24750573.2019.1695994
Publication status	Published - Oct 2 2019

All Science Journal Classification (ASJC) codes

Psychiatry and Mental health
Pharmacology (medical)

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Park, S. C., Jang, E. Y., Kim, K., Lee, H., Choi, J., Dan, A., Hussain, A., Tanra, A. J., Kato, T. A., Chee, K. Y., Lin, S. K., Tan, C. H., Javed, A., Sartorius, N., Shinfuku, N., & Park, Y. C. (2019). Establishing the cut-off scores for the severity ranges of schizophrenia on the BPRS-6 scale: findings from the REAP-AP. Psychiatry and Clinical Psychopharmacology, 29(4), 895-898. https://doi.org/10.1080/24750573.2019.1695994

Establishing the cut-off scores for the severity ranges of schizophrenia on the BPRS-6 scale : findings from the REAP-AP. / Park, Seon Cheol; Jang, Eun Young; Kim, Kiwon; Lee, Hoseon; Choi, Joonho; Dan, Amitava; Hussain, Arshad; Tanra, Andi Jayalangkara; Kato, Takahiro A.; Chee, Kok Yoon; Lin, Sih Ku; Tan, Chay Hoon; Javed, Afzal; Sartorius, Norman; Shinfuku, Naotaka; Park, Yong Chon.

In: Psychiatry and Clinical Psychopharmacology, Vol. 29, No. 4, 02.10.2019, p. 895-898.

Research output: Contribution to journal › Article › peer-review

Park, SC, Jang, EY, Kim, K, Lee, H, Choi, J, Dan, A, Hussain, A, Tanra, AJ, Kato, TA, Chee, KY, Lin, SK, Tan, CH, Javed, A, Sartorius, N, Shinfuku, N & Park, YC 2019, 'Establishing the cut-off scores for the severity ranges of schizophrenia on the BPRS-6 scale: findings from the REAP-AP', Psychiatry and Clinical Psychopharmacology, vol. 29, no. 4, pp. 895-898. https://doi.org/10.1080/24750573.2019.1695994

Park, Seon Cheol ; Jang, Eun Young ; Kim, Kiwon ; Lee, Hoseon ; Choi, Joonho ; Dan, Amitava ; Hussain, Arshad ; Tanra, Andi Jayalangkara ; Kato, Takahiro A. ; Chee, Kok Yoon ; Lin, Sih Ku ; Tan, Chay Hoon ; Javed, Afzal ; Sartorius, Norman ; Shinfuku, Naotaka ; Park, Yong Chon. / Establishing the cut-off scores for the severity ranges of schizophrenia on the BPRS-6 scale : findings from the REAP-AP. In: Psychiatry and Clinical Psychopharmacology. 2019 ; Vol. 29, No. 4. pp. 895-898.

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abstract = "Objective: Using data from the Research on Asian Psychotropic Prescription Patterns for Antipsychotics (REAP-AP), our study aimed to establish the remission and severity ranges (mild, moderate, and severe) of schizophrenia on the Brief Psychiatric Rating Scale-6 (BPRS-6). Methods: A total of 1,438 patients with schizophrenia from India, Indonesia, Japan, Malaysia, and Taiwan were enrolled in the study. Using the receiver operating characteristic (ROC) curve analyses, the optimal cut-off scores for the remission and severity ranges on the BPRS-6 were established. Results: The scalability of the BPRS-6 was considered to have an acceptable “unidimensionality” (coefficient of scalability = 0.43). The cut-off scores for the remission of schizophrenia and mild, moderate, and severe schizophrenia can be optimally defined as the BPRS-6 total score of <5, 5–9, 10–19 and >20, respectively. Conclusion: The BPRS-6 can be a promising, brief, and unidimensional rating scale to supplement the measurement-based care of schizophrenia.",

author = "Park, {Seon Cheol} and Jang, {Eun Young} and Kiwon Kim and Hoseon Lee and Joonho Choi and Amitava Dan and Arshad Hussain and Tanra, {Andi Jayalangkara} and Kato, {Takahiro A.} and Chee, {Kok Yoon} and Lin, {Sih Ku} and Tan, {Chay Hoon} and Afzal Javed and Norman Sartorius and Naotaka Shinfuku and Park, {Yong Chon}",

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AU - Kato, Takahiro A.

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AU - Shinfuku, Naotaka

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