TY - JOUR
T1 - Establishment of a new human uterine cervical adenocarcinoma cell line, SiSo, and its
T2 - Reactivity to anti-cancer reagents
AU - Sonoda, K.
AU - Nakashima, M.
AU - Saito, T.
AU - Amada, S.
AU - Kamura, T.
AU - Nakano, H.
AU - Watanabe, T.
PY - 1995
Y1 - 1995
N2 - A human cell line, SiSo, was established from a patient afflicted with uterine cervical adenocarcinoma. The SiSo cell expresses MHC class I antigen, various kinds of adhesion molecules and tumor-associated antigens such as CA125, CEA and GA733. The secretion of CA125 antigen was markedly suppressed by anti-cancer reagents. However, their growth was not affected by any of the anti-cancer reagents tested, suggesting a discrepancy between inhibition of tumor growth and suppression of secretion of tumor-associated antigens after treatment with anti-cancer reagents. The SiSo cell line will provide a tool for investigation of uterine adenocarcinoma.
AB - A human cell line, SiSo, was established from a patient afflicted with uterine cervical adenocarcinoma. The SiSo cell expresses MHC class I antigen, various kinds of adhesion molecules and tumor-associated antigens such as CA125, CEA and GA733. The secretion of CA125 antigen was markedly suppressed by anti-cancer reagents. However, their growth was not affected by any of the anti-cancer reagents tested, suggesting a discrepancy between inhibition of tumor growth and suppression of secretion of tumor-associated antigens after treatment with anti-cancer reagents. The SiSo cell line will provide a tool for investigation of uterine adenocarcinoma.
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U2 - 10.3892/ijo.6.5.1099
DO - 10.3892/ijo.6.5.1099
M3 - Article
AN - SCOPUS:0028917598
SN - 1019-6439
VL - 6
SP - 1099
EP - 1104
JO - International Journal of Oncology
JF - International Journal of Oncology
IS - 5
ER -
