TY - JOUR
T1 - Estimation of magnetic moment and anisotropy energy of magnetic markers for biosensing application
AU - Enpuku, K.
AU - Sasayama, T.
AU - Yoshida, T.
PY - 2016/5/14
Y1 - 2016/5/14
N2 - We present a method to evaluate the magnetic moment (m) and the anisotropy energy (E) of magnetic markers, which are the key parameters employed in biosensing applications. The distributions of the m and E values in the marker are evaluated by analyzing the static magnetization (M-H) curve of the suspended markers and the frequency dependence of the AC susceptibility of the immobilized markers, respectively. Then, we obtain the relationship between m and E. In the experiment, four markers made of multicore and single core nanoparticles are examined. We obtain distributions of the m and E values, which show the particular characteristics of each marker. Although the m and E values are widely distributed in the marker, a clear relationship is obtained between the values. Therefore, the obtained m-E curve, as well as the distribution of the m and E values, provides a framework to discuss the dynamic behavior of the immobilized markers. The difference in the estimated m-E curves between the markers is also discussed.
AB - We present a method to evaluate the magnetic moment (m) and the anisotropy energy (E) of magnetic markers, which are the key parameters employed in biosensing applications. The distributions of the m and E values in the marker are evaluated by analyzing the static magnetization (M-H) curve of the suspended markers and the frequency dependence of the AC susceptibility of the immobilized markers, respectively. Then, we obtain the relationship between m and E. In the experiment, four markers made of multicore and single core nanoparticles are examined. We obtain distributions of the m and E values, which show the particular characteristics of each marker. Although the m and E values are widely distributed in the marker, a clear relationship is obtained between the values. Therefore, the obtained m-E curve, as well as the distribution of the m and E values, provides a framework to discuss the dynamic behavior of the immobilized markers. The difference in the estimated m-E curves between the markers is also discussed.
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U2 - 10.1063/1.4948951
DO - 10.1063/1.4948951
M3 - Article
AN - SCOPUS:84971273158
VL - 119
JO - Journal of Applied Physics
JF - Journal of Applied Physics
SN - 0021-8979
IS - 18
M1 - 184902
ER -