Evaluating adjunctive surgical procedures during vitrectomy for diabetic macular edema

Yasutaka Mochizuki, Yasuaki Hata, Hiroshi Enaida, Keizo Yoshiyama, Miho Miyazaki, Akifumi Ueno, Toshinori Murata, Taiji Sakamoto, Toshiaki Kubota, Tatsuro Ishibashi

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Abstract

PURPOSE: To evaluate the long-term outcomes of adjunctive surgical procedures during pars plana vitrectomy (PPV) for the treatment of diabetic macular edema (DME). METHODS: In this nonrandomized study, we retrospectively analyzed 57 eyes of 54 patients who had DME and had undergone PPV. We performed PPV using three different surgical procedures: conventional PPV (group PVD; 13 eyes), triamcinolone acetonide (TA)-assisted PPV (group TA; 22 eyes), and TA-assisted PPV combined with internal limiting membrane (ILM) peeling (group ILM; 22 eyes). We also evaluated the preoperative and postoperative best-corrected visual acuity (BCVA) results. RESULTS: The overall mean preoperative BCVA was 0.86 logarithm of the minimal angle of resolution unit. In groups PVD, TA, and ILM, BCVAs were 0.99, 0.90, and 0.74 (P = 0.310), respectively. The mean postoperative BCVA for all patients improved to 0.68 (P = 0.005). The postoperative BCVA improved in 47% of the treated eyes, it remained unchanged in 37% of the treated eyes, and it deteriorated in 16% of the treated eyes. However, we observed no significant difference in the mean postoperative BCVAs between the three groups. Furthermore, we found that there was no significant difference in postoperative BCVA improvements between any of the groups (P = 0.450). CONCLUSION: The present study suggests that these 3 PPV approaches do not significantly affect postoperative BCVAs after 18 months of DME treatment.

Original languageEnglish
Pages (from-to)143-148
Number of pages6
JournalRetina
Volume26
Issue number2
DOIs
Publication statusPublished - Feb 1 2006

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Temazepam
Macular Edema
Vitrectomy
Triamcinolone Acetonide
Visual Acuity
Membranes
Therapeutics

All Science Journal Classification (ASJC) codes

  • Ophthalmology

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Evaluating adjunctive surgical procedures during vitrectomy for diabetic macular edema. / Mochizuki, Yasutaka; Hata, Yasuaki; Enaida, Hiroshi; Yoshiyama, Keizo; Miyazaki, Miho; Ueno, Akifumi; Murata, Toshinori; Sakamoto, Taiji; Kubota, Toshiaki; Ishibashi, Tatsuro.

In: Retina, Vol. 26, No. 2, 01.02.2006, p. 143-148.

Research output: Contribution to journalArticle

Mochizuki, Y, Hata, Y, Enaida, H, Yoshiyama, K, Miyazaki, M, Ueno, A, Murata, T, Sakamoto, T, Kubota, T & Ishibashi, T 2006, 'Evaluating adjunctive surgical procedures during vitrectomy for diabetic macular edema', Retina, vol. 26, no. 2, pp. 143-148. https://doi.org/10.1097/00006982-200602000-00003
Mochizuki Y, Hata Y, Enaida H, Yoshiyama K, Miyazaki M, Ueno A et al. Evaluating adjunctive surgical procedures during vitrectomy for diabetic macular edema. Retina. 2006 Feb 1;26(2):143-148. https://doi.org/10.1097/00006982-200602000-00003
Mochizuki, Yasutaka ; Hata, Yasuaki ; Enaida, Hiroshi ; Yoshiyama, Keizo ; Miyazaki, Miho ; Ueno, Akifumi ; Murata, Toshinori ; Sakamoto, Taiji ; Kubota, Toshiaki ; Ishibashi, Tatsuro. / Evaluating adjunctive surgical procedures during vitrectomy for diabetic macular edema. In: Retina. 2006 ; Vol. 26, No. 2. pp. 143-148.
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AU - Hata, Yasuaki

AU - Enaida, Hiroshi

AU - Yoshiyama, Keizo

AU - Miyazaki, Miho

AU - Ueno, Akifumi

AU - Murata, Toshinori

AU - Sakamoto, Taiji

AU - Kubota, Toshiaki

AU - Ishibashi, Tatsuro

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N2 - PURPOSE: To evaluate the long-term outcomes of adjunctive surgical procedures during pars plana vitrectomy (PPV) for the treatment of diabetic macular edema (DME). METHODS: In this nonrandomized study, we retrospectively analyzed 57 eyes of 54 patients who had DME and had undergone PPV. We performed PPV using three different surgical procedures: conventional PPV (group PVD; 13 eyes), triamcinolone acetonide (TA)-assisted PPV (group TA; 22 eyes), and TA-assisted PPV combined with internal limiting membrane (ILM) peeling (group ILM; 22 eyes). We also evaluated the preoperative and postoperative best-corrected visual acuity (BCVA) results. RESULTS: The overall mean preoperative BCVA was 0.86 logarithm of the minimal angle of resolution unit. In groups PVD, TA, and ILM, BCVAs were 0.99, 0.90, and 0.74 (P = 0.310), respectively. The mean postoperative BCVA for all patients improved to 0.68 (P = 0.005). The postoperative BCVA improved in 47% of the treated eyes, it remained unchanged in 37% of the treated eyes, and it deteriorated in 16% of the treated eyes. However, we observed no significant difference in the mean postoperative BCVAs between the three groups. Furthermore, we found that there was no significant difference in postoperative BCVA improvements between any of the groups (P = 0.450). CONCLUSION: The present study suggests that these 3 PPV approaches do not significantly affect postoperative BCVAs after 18 months of DME treatment.

AB - PURPOSE: To evaluate the long-term outcomes of adjunctive surgical procedures during pars plana vitrectomy (PPV) for the treatment of diabetic macular edema (DME). METHODS: In this nonrandomized study, we retrospectively analyzed 57 eyes of 54 patients who had DME and had undergone PPV. We performed PPV using three different surgical procedures: conventional PPV (group PVD; 13 eyes), triamcinolone acetonide (TA)-assisted PPV (group TA; 22 eyes), and TA-assisted PPV combined with internal limiting membrane (ILM) peeling (group ILM; 22 eyes). We also evaluated the preoperative and postoperative best-corrected visual acuity (BCVA) results. RESULTS: The overall mean preoperative BCVA was 0.86 logarithm of the minimal angle of resolution unit. In groups PVD, TA, and ILM, BCVAs were 0.99, 0.90, and 0.74 (P = 0.310), respectively. The mean postoperative BCVA for all patients improved to 0.68 (P = 0.005). The postoperative BCVA improved in 47% of the treated eyes, it remained unchanged in 37% of the treated eyes, and it deteriorated in 16% of the treated eyes. However, we observed no significant difference in the mean postoperative BCVAs between the three groups. Furthermore, we found that there was no significant difference in postoperative BCVA improvements between any of the groups (P = 0.450). CONCLUSION: The present study suggests that these 3 PPV approaches do not significantly affect postoperative BCVAs after 18 months of DME treatment.

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